Cyclonerane Derivatives from the Algicolous Endophytic Fungus Trichoderma asperellum A-YMD-9-2

doi:10.3390/md17050252

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Cyclonerane Derivatives from the Algicolous Endophytic Fungus Trichoderma asperellum A-YMD-9-2
	Song, YP ; Miao, FP ; Liu, XH ; Yin, XL ; Ji, NY
刊名	MARINE DRUGS
	2019-05
卷号	17 期号:5 页码:252
关键词	Trichoderma asperellum sesquiterpene cyclonerane
ISSN号	1660-3397
DOI	10.3390/md17050252
产权排序	[Song, Yin-Ping ; Miao, Feng-Ping ; Liu, Xiang-Hong ; Yin, Xiu-Li ; Ji, Nai-Yun] Yantai Inst Coastal Zone Res, Chinese Acad Sci, Yantai 264003, Peoples R China ; [Song, Yin-Ping ; Liu, Xiang-Hong] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China ; [Song, Yin-Ping ; Miao, Feng-Ping ; Liu, Xiang-Hong ; Yin, Xiu-Li ; Ji, Nai-Yun] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
文献子类	Article
英文摘要	Seven previously unreported cyclonerane derivatives, namely, 3,7,11-trihydroxycycloneran-10-one, cycloneran-3,7,10,11-tetraol, cycloneran-3,7,11-triol, 11,12,15-trinorcycloneran-3,7,10-triol, 7,10S-epoxycycloneran-3,15-diol, 7,10R-epoxycycloneran-3,15-diol, and (10Z)-15-acetoxy-10-cycloneren-3,7-diol, were isolated in addition to the known (10Z)-cyclonerotriol, (10E)-cyclonerotriol, catenioblin C, and chokol E from the culture of Trichoderma asperellum A-YMD-9-2, an endophytic fungus obtained from the marine red alga Gracilaria verrucosa. The structures of previously unreported compounds were established by spectroscopic techniques, including 1D/2D NMR, MS, and IR. The isolation of these new cyclonerane derivatives greatly adds to the structural diversity of unusual cyclonerane sesquiterpenes, and several isolates exhibit potent inhibition against some marine phytoplankton species.
WOS关键词	ABSOLUTE-CONFIGURATION ; SESQUITERPENOIDS ; METABOLITES ; ATROVIRIDE ; DITERPENES
WOS研究方向	Chemistry, Medicinal
语种	英语
WOS记录号	WOS:000470964600005
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31670355] ; Natural Science Foundation for Distinguished Young Scholars of Shandong Province [JQ201712] ; Key Cutting-Edge Research Program of the CAS [QYZDB-SSW-DQC013] ; Science and Technology Service Network Initiative of the CAS [KFJ-STS-ZDTP-023] ; Youth Innovation Promotion Association of the CAS [2013138]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24943]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Yantai Inst Coastal Zone Res, Chinese Acad Sci, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China; 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Song, YP,Miao, FP,Liu, XH,et al. Cyclonerane Derivatives from the Algicolous Endophytic Fungus Trichoderma asperellum A-YMD-9-2[J]. MARINE DRUGS,2019,17(5):252.
APA	Song, YP,Miao, FP,Liu, XH,Yin, XL,&Ji, NY.(2019).Cyclonerane Derivatives from the Algicolous Endophytic Fungus Trichoderma asperellum A-YMD-9-2.MARINE DRUGS,17(5),252.
MLA	Song, YP,et al."Cyclonerane Derivatives from the Algicolous Endophytic Fungus Trichoderma asperellum A-YMD-9-2".MARINE DRUGS 17.5(2019):252.