Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts

doi:10.1016/j.ijbiomac.2018.06.018

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts
	Zhang, Jingjing ; Tan, Wenqiang ; Wang, Gang ; Yin, Xiuli ; Li, Qing ; Dong, Fang ; Guo, Zhanyong
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2018-10-15
卷号	118 期号:A 页码:9-14
关键词	Antioxidant activity N,N,N-trimethyl chitosan salts Structure characteristics
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2018.06.018
产权排序	[Zhang, Jingjing ; Tan, Wenqiang ; Wang, Gang ; Yin, Xiuli ; Li, Qing ; Dong, Fang ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Zhang, Jingjing ; Tan, Wenqiang ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
文献子类	Article
英文摘要	Chitosan, possessing excellent properties, has been drawing broad attention. For the further utilization of chitosan, chemical modification is performed in improving its water solubility and the bioactivities. In the current study, four N,N,N-trimethyl chitosan salts, including N,N,N-trimethyl chitosan citrate (TMCSCi), N,N,N-trimethyl chitosan acetylsalicylate (TMCSAc), N,N,N-trimethyl chitosan ascorbate (TMCSAs), and N,N,N-trimethyl chitosan gallate (TMCSGa), were prepared via N,N,N-trimethyl chitosan iodide (TMCSI). The as-prepared products were characterized by FT-IR and H-1 NMR. Meanwhile, the degrees of substitution were calculated by elemental analysis results. Furthermore, scavenging activities (against DPPH radicals and superoxide radicals) test and reducing power test were selected to evaluate the antioxidant property of N,N,N-trimethyl chitosan salts in vitro. The results indicated that TMCSAs and TMCSGa displayed excellent activity, probably due to the enhancement of ascorbate and gallate in antioxidant activity. However, because of the weak antioxidant property of citrate and acetylsalicylate, the activity was lower for TMCSCi and TMCSAc. For example, in the DPPH radicals scavenging assay, the scavenging rates of chitosan, TMCSI, TMCSCi, TMCSAc, TMCSAs, and TMCSGa were 25.22, 84.11, 6.90, 2.70, 94.92, and 96.75% at 0.4 mg/mL, respectively. Generally, TMCSAs and TMCSGa could be regarded as a potential source of antioxidants. (C) 2018 Elsevier B.V. All rights reserved.
WOS关键词	ASCORBIC-ACID ; MOLECULAR-WEIGHT ; GALLIC ACID ; CITRIC-ACID ; IN-VITRO ; ANTIFUNGAL ; DERIVATIVES ; NANOPARTICLES ; RESPONSES ; PROPERTY
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
语种	英语
WOS记录号	WOS:000445170200002
资助机构	National Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of China [ZR2017BD015] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [2015418022-3]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24550]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_污染过程与控制实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Jingjing,Tan, Wenqiang,Wang, Gang,et al. Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,118(A):9-14.
APA	Zhang, Jingjing.,Tan, Wenqiang.,Wang, Gang.,Yin, Xiuli.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,118(A),9-14.
MLA	Zhang, Jingjing,et al."Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 118.A(2018):9-14.