Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)

doi:10.3389/fgene.2021.611570

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)
	Lyu, Ding 1,2,3; Yu, Yang 1,2,3; Wang, Quanchao 1,3,4; Luo, Zheng 1,3,5; Zhang, Qian 1,3,5; Zhang, Xiaojun 1,2,3; Xiang, Jianhai 1,3; Li, Fuhua 1,2,3,6
刊名	FRONTIERS IN GENETICS
	2021-04-07
卷号	12 页码:9
关键词	GWAS growth trait marker assisted BLUP genetic breeding Litopenaeus vannamei
DOI	10.3389/fgene.2021.611570
通讯作者	Li, Fuhua(fhli@qdio.ac.cn)
英文摘要	The Pacific white shrimp (Litopenaeus vannamei) is the most widely cultured shrimp in the world. A great attention has been paid to improve its body weight (BW) at harvest through genetic selection for decades. Genome-wide association study (GWAS) is a tool to dissect the genetic basis of the traits. In this study, a GWAS approach was conducted to find genes related to BW through genotyping 94,113 single nucleotide polymorphisms (SNPs) in 200 individuals from a breeding population. Four BW-related SNPs located in LG19 and LG39 were identified. Through further candidate gene association analysis, the SNPs in two candidate genes, deoxycytidylate deaminase and non-receptor protein tyrosine kinase, were found to be related with the body weight of the shrimp. Marker-assisted best linear unbiased prediction (MA-BLUP) based on the SNPs in these two genes was used to estimate the breeding values, and the result showed that the highest prediction accuracy of MA-BLUP was increased by 9.4% than traditional BLUP. These results will provide useful information for the marker-assisted breeding in L. vannamei.
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105] ; National Key R&D Program of China[2018YFD0901301] ; Agricultural Variety Improvement Project of Shandong Province[2019LZGC014] ; China Agriculture Research System-48[CARS-48]
WOS研究方向	Genetics & Heredity
语种	英语
WOS记录号	WOS:000641715100001
资助机构	Strategic Priority Research Program of the Chinese Academy of Sciences ; National Key R&D Program of China ; Agricultural Variety Improvement Project of Shandong Province ; China Agriculture Research System-48
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/27302]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Li, Fuhua
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China
推荐引用方式 GB/T 7714	Lyu, Ding,Yu, Yang,Wang, Quanchao,et al. Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)[J]. FRONTIERS IN GENETICS,2021,12:9.
APA	Lyu, Ding.,Yu, Yang.,Wang, Quanchao.,Luo, Zheng.,Zhang, Qian.,...&Li, Fuhua.(2021).Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei).FRONTIERS IN GENETICS,12,9.
MLA	Lyu, Ding,et al."Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)".FRONTIERS IN GENETICS 12(2021):9.