Proharziane and Harziane Derivatives from the Marine Algicolous Fungus Trichoderma asperelloides RR-dl-6-11

doi:10.1021/acs.jnatprod.1c00188

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Proharziane and Harziane Derivatives from the Marine Algicolous Fungus Trichoderma asperelloides RR-dl-6-11
	Zou, Ji-Xue 1,2; Song, Yin-Ping 1; Zeng, Zhao-Qing 3; Ji, Nai-Yun 1
刊名	JOURNAL OF NATURAL PRODUCTS
	2021-04-23
卷号	84 期号:4 页码:1414-1419
ISSN号	0163-3864
DOI	10.1021/acs.jnatprod.1c00188
通讯作者	Ji, Nai-Yun(nyji@yic.ac.cn)
英文摘要	One new proharziane and three new harziane derivatives (1-4) together with six known ones (5-10) were isolated from the marine-alga-derived ascomycete Trichoderma asperelloides RR-dl-6-11. Their structures and relative configurations were determined via spectroscopic techniques, and the absolute configurations were ascertained by analysis of ECD curves. This is the first report on the secondary metabolites of T. asperelloides, and the new isolates (1-4), especially seco-harziane 4, greatly add to the structural diversity of harziane diterpenes as well as their precursors and catabolites. Compounds 1-5 inhibited four marine phytoplankton species, and the structure-activity relationship of harziane derivatives is analyzed.
资助项目	Natural Science Foundation for Distinguished Young Scholars of Shandong Province[JQ201712] ; National Natural Science Foundation of China[42076096] ; Taishan Scholar Project Special Funding[tsqn201909164]
WOS关键词	SCLEROTINIA-SCLEROTIORUM ; BIOLOGICAL-CONTROL ; SESQUITERPENES ; CYCLONERANE ; DITERPENES ; SELECTION ; STRAINS
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000644478400052
资助机构	Natural Science Foundation for Distinguished Young Scholars of Shandong Province ; National Natural Science Foundation of China ; Taishan Scholar Project Special Funding
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/27274]
专题	海岸带生物学与生物资源利用重点实验室烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室海岸带生物资源高效利用研究与发展中心
通讯作者	Ji, Nai-Yun
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Microbiol, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Zou, Ji-Xue,Song, Yin-Ping,Zeng, Zhao-Qing,et al. Proharziane and Harziane Derivatives from the Marine Algicolous Fungus Trichoderma asperelloides RR-dl-6-11[J]. JOURNAL OF NATURAL PRODUCTS,2021,84(4):1414-1419.
APA	Zou, Ji-Xue,Song, Yin-Ping,Zeng, Zhao-Qing,&Ji, Nai-Yun.(2021).Proharziane and Harziane Derivatives from the Marine Algicolous Fungus Trichoderma asperelloides RR-dl-6-11.JOURNAL OF NATURAL PRODUCTS,84(4),1414-1419.
MLA	Zou, Ji-Xue,et al."Proharziane and Harziane Derivatives from the Marine Algicolous Fungus Trichoderma asperelloides RR-dl-6-11".JOURNAL OF NATURAL PRODUCTS 84.4(2021):1414-1419.