Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging

doi:10.1021/acsami.8b06253

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室 > 近岸生态与环境实验室

	Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging
	Mei, Rongchao 1,3; Wang, Yunqing 1,3; Liu, Wanhui 3; Chen, Lingxin 1,2
刊名	ACS APPLIED MATERIALS & INTERFACES
	2018-07-18
卷号	10 期号:28 页码:23605-23616
关键词	gold nanoparticle core-satellite nanoparticle in situ growth lipid bilayer surface-enhanced Raman scattering tags bioimaging
ISSN号	1944-8244
DOI	10.1021/acsami.8b06253
产权排序	[Mei, Rongchao ; Wang, Yunqing ; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China ; [Mei, Rongchao ; Wang, Yunqing ; Liu, Wanhui] Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China ; [Chen, Lingxin] Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China
文献子类	Article
英文摘要	Herein, we presented waxberry-like core satellite (C-S) nanoparticles (NPs) prepared by an in situ growth of satellite gold NPs on spherical phospholipid bilayer-coated gold cores. The fluidic lipid bilayer cross-linker was reported for the first time, which imparted several novel morphological and optical properties to the C-S NPs. First, it regulated the anisotropic growth of the satellite NPs into vertically oriented nanorods on the core NP surface. Thus, an interesting waxberry-like nanostructure could be obtained, which was different from the conventional raspberry-like C-S structures decorated with spherical satellite NPs. Second, the satellite NPs were "soft-landed" on the lipid bilayer and could move on the core NP surface under certain conditions. The movement induced tunable plasmonic features in the C-S NPs. Furthermore, the fluidic lipid bilayer was capable of not only holding an abundance of reporter molecules but also delivering them to the hotspots at the junctions between the core and satellite NPs, which made the C-S NPs an excellent candidate for preparing ultrasensitive surface-enhanced Raman scattering (SERS) tags. The bioimaging capabilities of the C-S NP-based SERS tags were successfully demonstrated in living cells and mice. The developed SERS tags hold great potential for bioanalysis and medical diagnostics.
WOS关键词	GOLD NANOPARTICLES ; SERS TAGS ; PLASMONIC SUPERSTRUCTURES ; PHOSPHOLIPID-BILAYERS ; PHOTOTHERMAL THERAPY ; OPTICAL-PROPERTIES ; SPECTROSCOPY ; ASSEMBLIES ; LIPOSOMES ; CANCER
WOS研究方向	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
语种	英语
WOS记录号	WOS:000439528400021
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24435]
专题	烟台海岸带研究所_近岸生态与环境实验室烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn Technol Shandong Pr, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; 2.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China 3.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China;
推荐引用方式 GB/T 7714	Mei, Rongchao,Wang, Yunqing,Liu, Wanhui,et al. Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging[J]. ACS APPLIED MATERIALS & INTERFACES,2018,10(28):23605-23616.
APA	Mei, Rongchao,Wang, Yunqing,Liu, Wanhui,&Chen, Lingxin.(2018).Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging.ACS APPLIED MATERIALS & INTERFACES,10(28),23605-23616.
MLA	Mei, Rongchao,et al."Lipid Bilayer-Enabled Synthesis of Waxberry-like Core-Fluidic Satellite Nanoparticles: Toward Ultrasensitive Surface-Enhanced Raman Scattering Tags for Bioimaging".ACS APPLIED MATERIALS & INTERFACES 10.28(2018):23605-23616.