Targets such as plastic bags can absorb a lot of high-energy lasers which fired from the laser in a long distance. By aligning the laser center with the optical center of the high definition camera, we can determine that the laser emission point is located at the center of video. We can adjust the angle and position of the camera to make the video center coincide with the target, and finally accurately clean up the target from a long distance. In the process of video, this paper uses the target tracking algorithm based on template and the abnormal target detection method based on inter-frame difference. After we lock the target to be cleaned in a frame, the system can automatically calculate the angle and distance if the target swings in the wind, and send the corresponding motion command to the rotating device which can drive the camera to move, finally realize the target tracking and cleaning. Abnormal target detection algorithm is used to monitor the designated area near the target while emitting high-energy laser. When abnormal target such as human is found to enter, protection mechanism is triggered in time to turn off laser which can prevent dangerous accidents. © 2019 SPIE.