Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform

doi:10.1002/ange.201911113

CORC > 合肥物质科学研究院 > 中国科学院合肥物质科学研究院 > 中科院等离子体物理研究所

	Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform
	Zhang, Dailiang 3; Wang, Linlin 3; Yuan, Xi 3; Gong, Yijun 6; Liu, Hongwen 3; Zhang, Jing 3; Zhang, Xiaobing 3; Liu, Yanlan 3; Tan, Weihong 1,2,3,4,5
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2020-01-07
卷号	59
关键词	anti-Stokes emission naked-eye readout NIR fluorescence response phosgene visualization detection
ISSN号	1433-7851
DOI	10.1002/ange.201911113
通讯作者	Liu, Yanlan(ylliu@hnu.edu.cn) ; Tan, Weihong(tan@hnu.edu.cn)
英文摘要	Fluorescence visualization (FV) in the near-infrared (NIR) window promises to break through the signal-to-background ratio (SBR) bottleneck of traditional visible-light-driven FV methods. However, straightforward NIR-FV has not been realized, owing to the lack of methods to readily transduce NIR responses into instrument-free, naked eye-recognizable outputs. Now, an initiation-input-transduction platform comprising a well-designed NIR fluorophore as the signal initiator and lanthanide-doped nanocrystals as the transducer for facile NIR-FV is presented. The analyte-induced off-on NIR signal serves as a sensitizing switch of transducer visible luminescence for naked-eye readout. The design is demonstrated for portable, quantitative detection of phosgene with significantly improved SBR and sensitivity. By further exploration of initiators, this strategy holds promise to create advanced NIR-FV probes for broad sensing applications.
资助项目	National Natural Science Foundation of China[NSFC21827811] ; National Natural Science Foundation of China[61527806] ; National Natural Science Foundation of China[21877031] ; Science and Technology Innovation Program of Hunan Province[2017XK2103] ; Science and Technology Innovation Program of Hunan Province[2018RS3043] ; Young Thousand Talented Program
WOS关键词	SENSITIZED UP-CONVERSION ; VISUALIZATION ; PROBE ; CHEMOSENSORS ; PHOSGENE
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000505279500024
资助机构	National Natural Science Foundation of China ; Science and Technology Innovation Program of Hunan Province ; Young Thousand Talented Program
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/42774]
专题	合肥物质科学研究院_中科院等离子体物理研究所
通讯作者	Liu, Yanlan; Tan, Weihong
作者单位	1.Univ Chinese Acad Sci, Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China 2.Chinese Acad Sci, IBMC, Hangzhou 310022, Zhejiang, Peoples R China 3.Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Biol,Aptamer Engn Ctr Hunan Prov, Mol Sci & Biomed Lab MBL,Coll Chem & Chem Engn, Changsha 410082, Peoples R China 4.Shanghai Jiao Tong Univ, State Key Lab Oncogenes & Related Genes, Renji Hosp, Sch Med,IMM, Shanghai 200240, Peoples R China 5.Shanghai Jiao Tong Univ, Coll Chem & Chem Engn, Shanghai 200240, Peoples R China 6.Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Dailiang,Wang, Linlin,Yuan, Xi,et al. Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2020,59.
APA	Zhang, Dailiang.,Wang, Linlin.,Yuan, Xi.,Gong, Yijun.,Liu, Hongwen.,...&Tan, Weihong.(2020).Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,59.
MLA	Zhang, Dailiang,et al."Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 59(2020).