Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus

doi:10.1039/d1ra01085a

	Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus
	Wang, Shu 2,3; Shen, Wanzhu 1,4; Zheng, Shuai 1,4; Li, Zhigang 2; Wang, Chongwen 1,4; Zhang, Long 2,3; Liu, Yong 2,3
刊名	RSC ADVANCES
	2021-04-20
卷号	11
DOI	10.1039/d1ra01085a
通讯作者	Wang, Chongwen() ; Zhang, Long(zhanglong@aiofm.ac.cn) ; Liu, Yong(liuyong@aiofm.ac.cn)
英文摘要	This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO2-Au-QD tags for sensitive and quantitative detection of Staphylococcus aureus (S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method for S. aureus can reach 10(4) and 100 cells mL(-1), respectively.
资助项目	National Natural Science Foundation of China[81830101] ; Natural Science Foundation of Anhui Province[1908085QB85]
WOS关键词	DOT-SHELL NANOCOMPOSITES ; MAGNETIC NANOPARTICLES ; SERS ; IMMUNOASSAY ; BACTERIA ; PCR ; BIOMARKERS ; IGM/IGG ; CAPTURE
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000640769800029
资助机构	National Natural Science Foundation of China ; Natural Science Foundation of Anhui Province
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/122101]
专题	中国科学院合肥物质科学研究院
通讯作者	Wang, Chongwen; Zhang, Long; Liu, Yong
作者单位	1.Anhui Agr Univ, Hefei 230036, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei 230036, Peoples R China 3.Univ Sci & Technol China, Hefei 230036, Peoples R China 4.Beijing Inst Radiat Med, Beijing 100850, Peoples R China
推荐引用方式 GB/T 7714	Wang, Shu,Shen, Wanzhu,Zheng, Shuai,et al. Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus[J]. RSC ADVANCES,2021,11.
APA	Wang, Shu.,Shen, Wanzhu.,Zheng, Shuai.,Li, Zhigang.,Wang, Chongwen.,...&Liu, Yong.(2021).Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus.RSC ADVANCES,11.
MLA	Wang, Shu,et al."Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus".RSC ADVANCES 11(2021).