The Analgesic Effects of Static Magnetic Fields

doi:10.1002/bem.22323

	The Analgesic Effects of Static Magnetic Fields
	Fan, Yixiang 1,4; Ji, Xinmiao 4; Zhang, Lei 4; Zhang, Xin 1,2,3,4
刊名	BIOELECTROMAGNETICS
	2021-02-01
卷号	42
关键词	magnetic fields (MFs) negative effects pain management positive effects SMF parameters
ISSN号	0197-8462
DOI	10.1002/bem.22323
通讯作者	Zhang, Xin(xinzhang@hmfl.ac.cn)
英文摘要	Pain is one of the most common reasons why people seek medical care, which is related to most disease states. Magnetic fields (MFs) can be applied locally to specific parts of human bodies with high penetration and temporal control, which have a long-debated history in folk therapy. The purpose of this review is to collect and analyze experimental data about the analgesic effects of static magnetic fields (SMFs) so that we can have a scientific understanding regarding this topic. We collected 28 studies (25 English and 3 Chinese papers) with proper sham controls that investigated the effects of SMFs on pain relief in humans or mice. We found that 64% of the human studies and all mice studies in the literature showed positive analgesic effects of SMFs, which are related to factors including SMF intensity, treatment time, and pain types. Higher intensity and/or longer treatment time, as well as some specific pain types, may have better pain relief effects. Initial mechanistic studies indicated that membrane receptors, such as capsaicin receptor VR1/TRPV1, opioid receptors, and P2X3 receptors, might be involved. By describing experimental evidence and analysis, we found that SMFs actually hold considerable promise for managing some specific types of pain if proper SMF parameters are used. More studies comprehensively evaluating the parameters of SMF and its corresponding analgesic effects on different pain types, as well as the underlying molecular mechanisms, will be necessary to further validate its therapeutic potential in pain management in the future. Bioelectromagnetics. 00:00-00, 2021. (c) 2021 Bioelectromagnetics Society
资助项目	Heye Health Technology Foundation[HYJJ20190801] ; Chinese Academy of Sciences Hefei Institutes of Physical Science (CASHIPS) Director's Fund[YZJJ201704]
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Biophysics
语种	英语
出版者	WILEY
WOS记录号	WOS:000612793100002
资助机构	Heye Health Technology Foundation ; Chinese Academy of Sciences Hefei Institutes of Physical Science (CASHIPS) Director's Fund
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/119751]
专题	中国科学院合肥物质科学研究院
通讯作者	Zhang, Xin
作者单位	1.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Hefei, Peoples R China 2.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei, Peoples R China 3.Int Magnetobiol Frontier Res Ctr iMFRC, Sci Isl, Hefei, Peoples R China 4.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Key Lab High Magnet Field & Ion Beam Phys Biol, 350 Shushanhu Rd, Hefei 230031, Peoples R China
推荐引用方式 GB/T 7714	Fan, Yixiang,Ji, Xinmiao,Zhang, Lei,et al. The Analgesic Effects of Static Magnetic Fields[J]. BIOELECTROMAGNETICS,2021,42.
APA	Fan, Yixiang,Ji, Xinmiao,Zhang, Lei,&Zhang, Xin.(2021).The Analgesic Effects of Static Magnetic Fields.BIOELECTROMAGNETICS,42.
MLA	Fan, Yixiang,et al."The Analgesic Effects of Static Magnetic Fields".BIOELECTROMAGNETICS 42(2021).