Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review

doi:10.1088/2058-6272/ab9ddd

	Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review
	Xu, Zimu 3,4,5,6; Lan, Yan 3,4,5; Ma, Jie 3,4; Shen, Jie 3,4,5; Han, Wei 3,4; Hu, Shuheng 6; Ye, Chaobing 6; Xi, Wenhao 5; Zhang, Yudi 6; Yang, Chunjun 2
刊名	PLASMA SCIENCE & TECHNOLOGY
	2020-10-01
卷号	22
关键词	atmospheric pressure plasma plasma medicine reactive species bacteria cancer cells
ISSN号	1009-0630
DOI	10.1088/2058-6272/ab9ddd
通讯作者	Hu, Shuheng(hushuheng@hfut.edu.cn) ; Yang, Chunjun(yangchunjun9@163.com) ; Cheng, Cheng(chengcheng@ipp.ac.cn)
英文摘要	Atmospheric pressure cold plasma, with advantages such as high particle activity, no thermal damage, high efficiency and direct and friendly contact with human tissues, is considered to have great potential in biomedical applications. Therefore, 'plasma medicine' as a new interdiscipline has been developed in the past two decades. This review first briefly describes the development of typical plasma sources suitable for biomedical applications, and those with different discharge forms are simply compared, evaluated and summarized. Subsequently, measurement of the crucial gaseous reactive particles (e.g. OH and O) and their spatio-temporal distributions are introduced. Meanwhile, the generation and variation rules and the related critical macroscopic parameters of the plasma-induced aqueous reactive species are summarized. Finally, related studies in the last ten years on the mechanisms of the plasma-driven microbial inactivation and plasma-induced apoptosis of cancer cells are introduced. Moreover, some scientific problems that need to be urgently solved in the field of plasma medicine are also discussed. This review will provide useful guidance for future related research.
资助项目	National Natural Science Foundation of China[51777206] ; National Natural Science Foundation of China[51807046] ; National Natural Science Foundation of China[51877208] ; Natural Science Foundation of Anhui Province[1908085MA29] ; Natural Science Foundation of Anhui Province[1808085MA13]
WOS关键词	DIELECTRIC BARRIER DISCHARGE ; COLD-PLASMA ; NONTHERMAL PLASMA ; ARGON PLASMA ; CELL-DEATH ; HYDROGEN-PEROXIDE ; STAPHYLOCOCCUS-AUREUS ; GOLD NANOPARTICLES ; MICROPLASMA JET ; CHRONIC WOUNDS
WOS研究方向	Physics
语种	英语
出版者	IOP PUBLISHING LTD
WOS记录号	WOS:000563246100001
资助机构	National Natural Science Foundation of China ; Natural Science Foundation of Anhui Province
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/70578]
专题	中国科学院合肥物质科学研究院
通讯作者	Hu, Shuheng; Yang, Chunjun; Cheng, Cheng
作者单位	1.Henan Univ Sci & Technol, Coll Med, Dept Med Genet, Luoyang 471023, Peoples R China 2.Anhui Med Univ, Affiliated Hosp 2, Dept Dermatol, Hefei 230601, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Anhui Prov Key Lab Med Phys & Technol, Hefei 230031, Peoples R China 4.Chinese Acad Sci, Ctr Med Phys & Technol, Hefei Inst Phys Sci, Hefei 230031, Peoples R China 5.Chinese Acad Sci, Inst Plasma Phys, Hefei Inst Phys Sci, Hefei 230031, Peoples R China 6.Hefei Univ Technol, Sch Resources & Environm Engn, Hefei 230009, Peoples R China
推荐引用方式 GB/T 7714	Xu, Zimu,Lan, Yan,Ma, Jie,et al. Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review[J]. PLASMA SCIENCE & TECHNOLOGY,2020,22.
APA	Xu, Zimu.,Lan, Yan.,Ma, Jie.,Shen, Jie.,Han, Wei.,...&Cheng, Cheng.(2020).Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review.PLASMA SCIENCE & TECHNOLOGY,22.
MLA	Xu, Zimu,et al."Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review".PLASMA SCIENCE & TECHNOLOGY 22(2020).