Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions

doi:10.1021/acs.nanolett.0c01058

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	Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions
	Xue CD ; Shi XH ; Tian Y ; Zheng X(郑旭); Hu GQ
刊名	NANO LETTERS
	2020-05-13
卷号	20 期号:5 页码:3895-3904
关键词	hopping diffusion DYNAMICS non-Gaussianity MOBILITY activated energy barrier ULTRASOUND crowded polymer solutions CHEMISTRY VISCOSITY ROTATION NANORODS
ISSN号	1530-6984
DOI	10.1021/acs.nanolett.0c01058
英文摘要	A long-distance hop of diffusive nanoparticles (NPs) in crowded environments was commonly considered unlikely, and its characteristics remain unclear. In this work, we experimentally identify the occurrence of the intermittent hops of large NPs in crowded entangled poly(ethylene oxide) (PEO) solutions, which are attributed to thermally induced activated hopping. We show that the diffusion of NPs in crowded solutions is considered as a superposition of the activated hopping and the reptation of the polymer solution. Such activated hopping becomes significant when either the PEO molecular weight is large enough or the NP size is relatively small. We reveal that the time-dependent non-Gaussianity of the NP diffusion is determined by the competition of the short-time relaxation of a polymer entanglement strand, the activated hopping, and the long-time reptation. We propose an exponential scaling law tau(hop)/tau(e) similar to exp(d/d(t)) to characterize the hopping time scale, suggesting a linear dependence of the activated hopping energy barrier on the dimensionless NP size. The activated hopping motion can only be observed between the onset time scale of the short-time relaxation of local entanglement strands and the termination time scale of the long-time relaxation. Our findings on activated hopping provide new insights into long-distance transportation of NPs in crowded biological environments, which is essential to the delivery and targeting of nanomedicines.
分类号	一类
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
WOS记录号	WOS:000535255300125
资助机构	Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [11832017, 11572335, 11572334, 11802054} ; Chinese Academy of Sciences Key Research Program of Frontier Sciences [QYZDB-SSW-JSC036} ; Chinese Academy of Sciences Strategic Priority Research Program [XDB22040403} ; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2019M651106}
其他责任者	Hu, GQ ; Zheng, X
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/85408]
专题	力学研究所_非线性力学国家重点实验室
作者单位	1.{Xue Chundong, Shi Xinghua} Univ Chinese Acad Sci Beijing 100149 Peoples R China 2.{Tian Yu} Tsinghua Univ State Key Lab Tribol Beijing 100084 Peoples R China 3.{Shi Xinghua} Natl Ctr Nanosci & Technol China Beijing 100190 Peoples R China 4.{Hu Guoqing} Zhejiang Univ Dept Engn Mech Hangzhou 310027 Zhejiang Peoples R China 5.{Hu Guoqing} Zhejiang Univ State Key Lab Fluid Power & Mechatron Syst Hangzhou 310027 Zhejiang Peoples R China 6.{Xue Chundong, Zheng Xu} Chinese Acad Sci State Key Lab Nonlinear Mech Inst Mech Beijing 100190 Peoples R China 7.{Xue Chundong} Dalian Univ Technol Sch Optoelect Engn & Instrumentat Sci Dalian 116024 Liaoning Peoples R China
推荐引用方式 GB/T 7714	Xue CD,Shi XH,Tian Y,et al. Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions[J]. NANO LETTERS,2020,20(5):3895-3904.
APA	Xue CD,Shi XH,Tian Y,郑旭,&Hu GQ.(2020).Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions.NANO LETTERS,20(5),3895-3904.
MLA	Xue CD,et al."Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions".NANO LETTERS 20.5(2020):3895-3904.