Acoapetaludines A-K, C-20 and C-19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch

doi:10.1016/j.phytochem.2019.112111

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	Acoapetaludines A-K, C-20 and C-19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch
	Hu, ZX (Hu, Zhan-Xing)[ 1,2,3,4,5,6 ]; An, Q (An, Qiao)[ 4,5,6 ]; Tang, HY (Tang, Hong-Yu)[ 1,7 ]; Chen, ZH (Chen, Zheng-Hong)[ 8 ]; Aisa, HA (Aisa, Haji Aker)[ 2 ]; Zhang, Y (Zhang, Yu)[ 1 ]; Hao, XJ (Hao, Xiao-Jiang)[ 1,4,5,6 ]
刊名	PHYTOCHEMISTRY
	2019
卷号	167 期号:11 页码:1-8
关键词	Aconitum apetalum (Huth) B.Fedtsch. (Ranunculaceae) Diterpenoid alkaloids Acoapetaludine A Anti-Helicobacter pylori
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2019.112111
英文摘要	A C-20-diterpenoid alkaloid with an unprecedented carbon skeleton, acoapetaludine A, together with ten undescribed aconitine-type C-19-diterpenoid alkaloids, acoapetaludines B-K, were isolated from the whole plants of Aconitum apetalum (Huth) B. Fedtsch. (Ranunculaceae). The structures were elucidated based on a comprehensive spectroscopic data analysis. The absolute configuration of acoapetaludine A was determined by quantum ECD calculation. Acoapetaludines D and E exhibited weak anti-Helicobacter pylori activity at a minimum inhibitory concentration (MIC) of 100 and 50 mu g/mL, respectively.
WOS记录号	WOS:000491607600014
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/7148]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室新疆理化技术研究所_资源化学研究室
作者单位	1.Guizhou Med Univ, Sch Basic Med Sci, Guiyang 550025, Guizhou, Peoples R China 2.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China 3.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China 4.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China 5.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China 6.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China 7.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China 8.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Hu, ZX ,An, Q ,Tang, HY ,et al. Acoapetaludines A-K, C-20 and C-19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch[J]. PHYTOCHEMISTRY,2019,167(11):1-8.
APA	Hu, ZX .,An, Q .,Tang, HY .,Chen, ZH .,Aisa, HA .,...&Hao, XJ .(2019).Acoapetaludines A-K, C-20 and C-19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch.PHYTOCHEMISTRY,167(11),1-8.
MLA	Hu, ZX ,et al."Acoapetaludines A-K, C-20 and C-19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch".PHYTOCHEMISTRY 167.11(2019):1-8.