Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents

doi:10.1016/j.bmcl.2005.08.046

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	Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents
	Wang, WL ; Yao, DY ; Gu, M; Fan, MZ ; Li, JY; Xing, YC ; Nan, FJ
刊名	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
	2005-12-01
卷号	15 期号:23 页码:5284-5287
关键词	synthesis bisheterocycle-containing compounds anti-influenza virus
ISSN号	0960-894X
DOI	10.1016/j.bmcl.2005.08.046
文献子类	Article
英文摘要	A series of novel 4,2-bisheterocycle tandem derivatives consisting of a methyloxazole and thiazole subunit were synthesized. Many compounds were found to inhibit human influenza A virus. Several analogues exhibited moderate biological activity and could serve as leads for further optimizations for antivirus research. (c) 2005 Elsevier Ltd. All rights reserved.
WOS关键词	MARINE SPONGE ; LEUCAMIDE-A ; BLEOMYCIN ; CLEAVAGE ; BINDING ; ANALOGS
WOS研究方向	Pharmacology & Pharmacy ; Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000232959300036
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273757]
专题	国家新药筛选中心
通讯作者	Nan, FJ
作者单位	1.Qingdao Univ, Coll Chem Engn, Shandong 266071, Peoples R China 2.Chinese Acad Sci, Chinese Natl Ctr Drug Screening, Shanghai Inst Mat Med, Shanghai Inst Biol Sci,Grad Sch, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Wang, WL,Yao, DY,Gu, M,et al. Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2005,15(23):5284-5287.
APA	Wang, WL.,Yao, DY.,Gu, M.,Fan, MZ.,Li, JY.,...&Nan, FJ.(2005).Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,15(23),5284-5287.
MLA	Wang, WL,et al."Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15.23(2005):5284-5287.