Four New Depsides Isolated from and Their Significant Nerve-Protective Activities

doi:10.3390/molecules23123274

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	Four New Depsides Isolated from and Their Significant Nerve-Protective Activities
	Jin, Qinghao; Hu, Xinyi; Deng, Yanping; Hou, Jinjun; Lei, Min; Ji, Hongjian; Zhou, Jing; Qu, Hua; Wu, Wanying; Guo, Dean
刊名	Molecules (Basel, Switzerland)
	2018-12-11
卷号	23 期号:12
ISSN号	1420-3049
DOI	10.3390/molecules23123274
文献子类	Article
英文摘要	By investigating of the roots of , which is one of the most widely used Chinese herbs, we used phytochemical methods successfully to obtain twelve depsides: four depsides (⁻) that were previously undescribed, along with eight known ones (⁻). Their structure characteristics were assessed by HR-ESIMS, CD, NMR (¹H, C, HSQC, HMBC) data analyses. These four newly isolated compounds (⁻), as well as the other eight compounds (⁻), show extraordinary protective effects on hydrogen peroxide-induced apoptosis in HS-SY5Y cells. Among them, depside and depside displayed more obviously protective effects than others.
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266792]
专题	上海中药现代化研究中心
通讯作者	Jin, Qinghao; Hu, Xinyi; Deng, Yanping; Hou, Jinjun; Lei, Min; Ji, Hongjian; Zhou, Jing; Qu, Hua; Wu, Wanying; Guo, Dean
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai 201203, China
推荐引用方式 GB/T 7714	Jin, Qinghao,Hu, Xinyi,Deng, Yanping,et al. Four New Depsides Isolated from and Their Significant Nerve-Protective Activities[J]. Molecules (Basel, Switzerland),2018,23(12).
APA	Jin, Qinghao.,Hu, Xinyi.,Deng, Yanping.,Hou, Jinjun.,Lei, Min.,...&Guo, Dean.(2018).Four New Depsides Isolated from and Their Significant Nerve-Protective Activities.Molecules (Basel, Switzerland),23(12).
MLA	Jin, Qinghao,et al."Four New Depsides Isolated from and Their Significant Nerve-Protective Activities".Molecules (Basel, Switzerland) 23.12(2018).