Serratene-type triterpenoids from Palhinhaea cernua

doi:10.1016/j.fitote.2018.02.011

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	Serratene-type triterpenoids from Palhinhaea cernua
	Wei, Jiao-Jiao 1,2; Wang, Wen-Qiong 1; Song, Wei-Bin 1; Xuan, Li-Jiang1
刊名	FITOTERAPIA
	2018-06
卷号	127 页码:151-158
关键词	Palhinhaea cernua Serratene triterpenoids Apoptosis
ISSN号	0367-326X
DOI	10.1016/j.fitote.2018.02.011
文献子类	Article
英文摘要	Phytochemical investigation of the 95% ethanol extract of the whole plant of Palhinhaea cernua afforded five new serratene-type triterpenoids (1-5) together with four known analogues (6-9). The structures of the new compounds were elucidated by extensive spectroscopic analysis and X-ray crystallographic data. Compounds 1-3 triggered apoptosis of Hela(-/-) cell with EC50 values of 3.49 +/- 0.05, 0.28 +/- 0.13 and 7.98 +/- 0.03 mu M, respectively.
资助项目	State Key Laboratory of Drug Research[SIMM1601ZZ-03] ; National Natural Science Foundation of China[81473111]
WOS关键词	LYCOPODIUM-JAPONICUM ; XANTHINE-OXIDASE ; STEM BARK ; CHOLINESTERASE ; ALKALOIDS
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000437551000023
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279718]
专题	上海中药现代化研究中心中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Xuan, Li-Jiang
作者单位	1.Chinese Acad Sci, Inst Materia Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wei, Jiao-Jiao,Wang, Wen-Qiong,Song, Wei-Bin,et al. Serratene-type triterpenoids from Palhinhaea cernua[J]. FITOTERAPIA,2018,127:151-158.
APA	Wei, Jiao-Jiao,Wang, Wen-Qiong,Song, Wei-Bin,&Xuan, Li-Jiang.(2018).Serratene-type triterpenoids from Palhinhaea cernua.FITOTERAPIA,127,151-158.
MLA	Wei, Jiao-Jiao,et al."Serratene-type triterpenoids from Palhinhaea cernua".FITOTERAPIA 127(2018):151-158.