Straightforward Synthesis of Novel Difluorinated 2-Hydroxyl-Substituted Dihydroquinolones Through Selectfluor-triggered Annulation of 2-Aminoarylenaminones

doi:10.1002/slct.201801951

	Straightforward Synthesis of Novel Difluorinated 2-Hydroxyl-Substituted Dihydroquinolones Through Selectfluor-triggered Annulation of 2-Aminoarylenaminones
	Zhao, Qing-Lan 3; Xiang, Hao-Yue 3; Yang, Chun-Hao1 ; Xiao, Jun-An 2; Xia, Peng-Ju 3; Chen, Xiao-Qing 3; Yang, Hua 3
刊名	CHEMISTRYSELECT
	2018-08-31
卷号	3 期号:32 页码:9218-9221
关键词	annulation cyclization difluorinated domino reactions quinolone
ISSN号	2365-6549
DOI	10.1002/slct.201801951
文献子类	Article
英文摘要	A series of novel difluorinated 2-hydroxyl-substituted dihydroquinolones have been firstly synthesized via selectfluor-triggered tandem cyclizations of 2-aminoarylenaminones. This new approach could occur under mild reaction conditions, and features easy operation and scalability.
资助项目	National Natural Science Foundation of China[21576296] ; National Natural Science Foundation of China[21676302] ; Natural Science Foundation of Hunan Province[2017JJ3401] ; State Key Laboratory of Drug Research[SIMM1705KF-15]
WOS关键词	ASYMMETRIC-SYNTHESIS ; O-HYDROXYARYLENAMINONES ; BIOLOGICAL EVALUATION ; MEDICINAL CHEMISTRY ; TANDEM CYCLIZATION ; FACILE ; ACCESS ; ACID ; 2-ARYL-2,3-DIHYDRO-4-QUINOLONES ; INHIBITORS
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000443225100007
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279608]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Xiang, Hao-Yue; Yang, Hua
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Guangxi Teachers Educ Univ, Coll Chem & Mat Sci, Nanning, Peoples R China 3.Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China;
推荐引用方式 GB/T 7714	Zhao, Qing-Lan,Xiang, Hao-Yue,Yang, Chun-Hao,et al. Straightforward Synthesis of Novel Difluorinated 2-Hydroxyl-Substituted Dihydroquinolones Through Selectfluor-triggered Annulation of 2-Aminoarylenaminones[J]. CHEMISTRYSELECT,2018,3(32):9218-9221.
APA	Zhao, Qing-Lan.,Xiang, Hao-Yue.,Yang, Chun-Hao.,Xiao, Jun-An.,Xia, Peng-Ju.,...&Yang, Hua.(2018).Straightforward Synthesis of Novel Difluorinated 2-Hydroxyl-Substituted Dihydroquinolones Through Selectfluor-triggered Annulation of 2-Aminoarylenaminones.CHEMISTRYSELECT,3(32),9218-9221.
MLA	Zhao, Qing-Lan,et al."Straightforward Synthesis of Novel Difluorinated 2-Hydroxyl-Substituted Dihydroquinolones Through Selectfluor-triggered Annulation of 2-Aminoarylenaminones".CHEMISTRYSELECT 3.32(2018):9218-9221.