Total Synthesis of Cytosporone B | |
Huang He; Zhang Lei; Zhang Xiaodong; Ji Xun; Ding Xiao; Shen Xu; Jiang Hualiang; Liu Hong1,2 | |
刊名 | CHINESE JOURNAL OF CHEMISTRY |
2010-06 | |
卷号 | 28期号:6页码:1041-1043 |
关键词 | Cytosporone B total synthesis agonist antitumor agents |
ISSN号 | 1001-604X |
DOI | 10.1002/cjoc.201090163 |
文献子类 | Article |
英文摘要 | The total synthesis of Cytosporone B, a naturally occurring agonist for Nur77, has been accomplished. The key steps are the sequential Grignard reaction and Lemieux-van Rudloff oxidation followed by a deprotection of the methyl aromatic ether to phenol and subsequent Friedel-Crafts acylation. |
资助项目 | National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[20872153] |
WOS关键词 | ORPHAN NUCLEAR RECEPTORS ; ENDOPHYTIC FUNGUS ; ACID-DERIVATIVES ; NUR77 ; DECARBOXYLATION ; DIFFERENTIATION ; ENDOCRINE ; COMPLEX |
WOS研究方向 | Chemistry |
语种 | 英语 |
CSCD记录号 | CSCD:3891202 |
出版者 | WILEY-BLACKWELL |
WOS记录号 | WOS:000279376200028 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/278884] |
专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Liu Hong |
作者单位 | 1.Chinese Acad Sci, Grad Sch, Shanghai 201203, Peoples R China 2.Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China; |
推荐引用方式 GB/T 7714 | Huang He,Zhang Lei,Zhang Xiaodong,et al. Total Synthesis of Cytosporone B[J]. CHINESE JOURNAL OF CHEMISTRY,2010,28(6):1041-1043. |
APA | Huang He.,Zhang Lei.,Zhang Xiaodong.,Ji Xun.,Ding Xiao.,...&Liu Hong.(2010).Total Synthesis of Cytosporone B.CHINESE JOURNAL OF CHEMISTRY,28(6),1041-1043. |
MLA | Huang He,et al."Total Synthesis of Cytosporone B".CHINESE JOURNAL OF CHEMISTRY 28.6(2010):1041-1043. |
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