Recent Developments in the Synthesis of Fluorine-Containing beta-Amino Acids and beta-Lactams
Lin Daizong; Wang Jiang; Liu Hong
刊名CHINESE JOURNAL OF ORGANIC CHEMISTRY
2013-10
卷号33期号:10页码:2098-2107
关键词fluorine-containing beta-amino acid fluorine-containing beta-lactam synthesis
ISSN号0253-2786
DOI10.6023/cjoc201303020
文献子类Review
英文摘要Fluorine-containing beta-amino acids and beta-lactams have attracted appreciable attention due to their wide application in organic chemistry, drug discovery, and protein biology. Accordingly, the development of efficient synthetic methods is of considerable interest in academia and industry. The synthesis and resolution are achieved. This review briefly summarizes the recent development in the methodologies for the synthesis of fluorine-containing beta-amino acids and beta-lactams with classification by the species of the fluorine-containing beta-amino acids (alpha-fluorinated beta-amino acids, alpha-trifluoromethyl beta-amino acids, and beta-trifluoromethyl beta-amino acids).
资助项目National Natural Science Foundation of China[81025017]
WOS关键词CONVENIENT ASYMMETRIC-SYNTHESIS ; SUBSTITUTED ALPHA,ALPHA-DIFLUORO-BETA-AMINO ACIDS ; ENANTIOSELECTIVE BIOMIMETIC TRANSAMINATION ; STEREOSELECTIVE-SYNTHESIS ; (R)-3-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID ; ETHYL BROMODIFLUOROACETATE ; REFORMATSKY REACTION ; RHODOPEPTIN ANALOGS ; MEDICINAL CHEMISTRY ; DIPEPTIDE ISOSTERES
WOS研究方向Chemistry
语种中文
CSCD记录号CSCD:4973038
出版者SCIENCE PRESS
WOS记录号WOS:000327365900005
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/277430]  
专题药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Lin Daizong
作者单位Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714
Lin Daizong,Wang Jiang,Liu Hong. Recent Developments in the Synthesis of Fluorine-Containing beta-Amino Acids and beta-Lactams[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2013,33(10):2098-2107.
APA Lin Daizong,Wang Jiang,&Liu Hong.(2013).Recent Developments in the Synthesis of Fluorine-Containing beta-Amino Acids and beta-Lactams.CHINESE JOURNAL OF ORGANIC CHEMISTRY,33(10),2098-2107.
MLA Lin Daizong,et al."Recent Developments in the Synthesis of Fluorine-Containing beta-Amino Acids and beta-Lactams".CHINESE JOURNAL OF ORGANIC CHEMISTRY 33.10(2013):2098-2107.
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