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	Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors
	Sun, Huiping1,2,3; Su, Jinghan1,2; Meng, Qingshuo1,2; Yin, Qi1,2; Chen, Lingli1,2; Gu, Wangwen1,2; Zhang, Pengcheng1,2; Zhang, Zhiwen1,2; Yu, Haijun1,2; Wang, Siling3
刊名	ADVANCED MATERIALS
	2016-11-16
卷号	28期号:43页码:9581-+
ISSN号	0935-9648
DOI	10.1002/adma.201602173
文献子类	Article
英文摘要	A unique biomimetic drug-delivery system composed of 4T1-breast-cancercell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung metastasis of the breast cancer cells.
资助项目	National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[81270047] ; National Basic Research Program of China[2013CB932704] ; National Basic Research Program of China[2012CB932502]
WOS关键词	BREAST-CANCER ; LUNG METASTASIS ; DRUG-DELIVERY ; AGGREGATION ; INHIBITION ; ANGIOGENESIS ; LIPOSOMES ; MEMBRANES ; GROWTH
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000391175000018
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/275806]
专题	药物制剂研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室
通讯作者	Wang, Siling; Li, Yaping
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, 501 Haike Rd, Shanghai 201203, Peoples R China; 3.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Sun, Huiping,Su, Jinghan,Meng, Qingshuo,et al. Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors[J]. ADVANCED MATERIALS,2016,28(43):9581-+.
APA	Sun, Huiping.,Su, Jinghan.,Meng, Qingshuo.,Yin, Qi.,Chen, Lingli.,...&Li, Yaping.(2016).Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.ADVANCED MATERIALS,28(43),9581-+.
MLA	Sun, Huiping,et al."Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors".ADVANCED MATERIALS 28.43(2016):9581-+.

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