Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis

doi:10.1002/hlca.200690012

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	Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis
	Yi, YH ; Xu, QZ ; Li, L; Zhang, SL ; Wu, HM ; Ding, J; Tong, YG ; Tan, WF ; Li, MH ; Tian, F
刊名	HELVETICA CHIMICA ACTA
	2006
卷号	89 期号:1 页码:54-63
ISSN号	0018-019X
DOI	10.1002/hlca.200690012
文献子类	Article
英文摘要	Two new sulfated triterpene glycosides, philinopsides A (1) and B (2), were isolated from the sea cucumber Pentacta quadrangularis. Their structures were established by extensive spectral analysis (2D-NMR and MS) and chemical evidence. Philinopside A (1) and B (2) showed significant cytotoxicity (ED50 0.75-3.50 mu g/ml) against ten tumor cell lines. Compound I also significantly inhibited the proliferation, migration, and tube formation of human microvascular endothelial cells.
WOS关键词	CUCUMARIA ; SAPONIN
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000234988100005
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273712]
专题	新药研究国家重点实验室中科院受体结构与功能重点实验室
通讯作者	Yi, YH
作者单位	1.Second Mil Med Univ, Res Ctr Marine Drugs, Sch Pharm, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Organ Chem, Div Antitumor Pharmacol, State Key Lab Drug Res, Shanghai 200031, Peoples R China 4.Univ N Carolina, Sch Pharm, Nat Prod Lab, Chapel Hill, NC 27599 USA
推荐引用方式 GB/T 7714	Yi, YH,Xu, QZ,Li, L,et al. Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis[J]. HELVETICA CHIMICA ACTA,2006,89(1):54-63.
APA	Yi, YH.,Xu, QZ.,Li, L.,Zhang, SL.,Wu, HM.,...&Lee, KH.(2006).Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis.HELVETICA CHIMICA ACTA,89(1),54-63.
MLA	Yi, YH,et al."Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis".HELVETICA CHIMICA ACTA 89.1(2006):54-63.