Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles

doi:10.1021/acs.orglett.7b01282

	Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles
	Ni, Jiabin 1,2,3; Zhao, Hongchuan 1,2,3; Zhang, Ao1,2,3
刊名	ORGANIC LETTERS
	2017-06-16
卷号	19 期号:12 页码:3159-3162
ISSN号	1523-7060
DOI	10.1021/acs.orglett.7b01282
文献子类	Article
英文摘要	A novel and efficient C-H activation approach for the direct 3,3-difhioroallylation of 2-pyridones and indoles is herein reported using a manganese(I) complex as the catalyst. A broad range of substrates with diverse functional groups were tolerated. Moreover late-stage C-H functionalization of bioactive molecules was achieved in good yield.
资助项目	Chinese NSF[81430080] ; Chinese NSF[81373277] ; National Program on Key Basic Research Project of China[2015CB910603] ; International Cooperative Program[GJHZ1622] ; Chinese Academy of Sciences[160621] ; Shanghai Commission of Science and Technology[16XD1404600] ; Shanghai Commission of Science and Technology[14431905300] ; Shanghai Commission of Science and Technology[14431900400]
WOS关键词	BOND ACTIVATION ; COBALT CATALYSIS ; DIRECTING GROUPS ; MANGANESE ; FUNCTIONALIZATION ; ALKYNES ; ESTERS ; ACID ; ALKENYLATION ; ALKYNYLATION
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000403854300031
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272603]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Zhang, Ao
作者单位	1.Chinese Acad Sci, SIMM, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Ni, Jiabin,Zhao, Hongchuan,Zhang, Ao. Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles[J]. ORGANIC LETTERS,2017,19(12):3159-3162.
APA	Ni, Jiabin,Zhao, Hongchuan,&Zhang, Ao.(2017).Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles.ORGANIC LETTERS,19(12),3159-3162.
MLA	Ni, Jiabin,et al."Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles".ORGANIC LETTERS 19.12(2017):3159-3162.