A new facile synthesis of shikalkin

doi:10.1016/j.cclet.2007.11.031

	A new facile synthesis of shikalkin
	Lu, Qun 2; Tang, Hao Lun 2; Shao, Yan Qiang 2; Cai, Jun Chao 1
刊名	CHINESE CHEMICAL LETTERS
	2008-02
卷号	19 期号:2 页码:172-174
关键词	synthesis shikalkin epoxides
ISSN号	1001-8417
DOI	10.1016/j.cclet.2007.11.031
文献子类	Article
英文摘要	A short and convergent approach for the synthesis of shikalkin (dl-shikonin) is presented. Stobbe reaction was employed to construct the aromatic skeleton 6. This is followed by a practical method to prepare the key epoxides 9 from aldehydes 8 in high yield. Finally, shikalkin is achieved by Grignard reaction and oxidation. (c) 2007 Qun Lu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
WOS关键词	LITHOSPERMUM-ERYTHRORHIZON ; SHIKONIN ; ALKANNIN ; DERIVATIVES ; INHIBITION ; INGREDIENT
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER SCIENCE INC
WOS记录号	WOS:000256867400013
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272990]
专题	中国科学院上海药物研究所
通讯作者	Lu, Qun
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.SW Jiaotong Univ, Dept Bioengn, Chengdu 610031, Peoples R China;
推荐引用方式 GB/T 7714	Lu, Qun,Tang, Hao Lun,Shao, Yan Qiang,et al. A new facile synthesis of shikalkin[J]. CHINESE CHEMICAL LETTERS,2008,19(2):172-174.
APA	Lu, Qun,Tang, Hao Lun,Shao, Yan Qiang,&Cai, Jun Chao.(2008).A new facile synthesis of shikalkin.CHINESE CHEMICAL LETTERS,19(2),172-174.
MLA	Lu, Qun,et al."A new facile synthesis of shikalkin".CHINESE CHEMICAL LETTERS 19.2(2008):172-174.