Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don

doi:10.1002/jssc.201800476

	Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don
	Qin, Zifei 1,3,4; Lin, Pei 3; Yao, Zhihong 3,4,5; Chen, Zilin 3; Yu, Yang 3,4; Dai, Yi 3,4; He, Xiangjiu 6; Zhou, Hua 2; Yao, Xinsheng 2,3,4
刊名	Journal of Separation Science
	2018-12
卷号	41 期号:23 页码:4253-4271
ISSN号	16159306
DOI	10.1002/jssc.201800476
文献子类	Article
英文摘要	Allium chinense G. Don, a popular edible condiment with reputation of Ganoderma lucidum in vegetables, exerts significant health effects for treating coronary disease but chemical compounds and corresponding contents still remain unclear. In this study, a total of 80 chemical compounds were detected in Allium chinense extracts based on a summarized fragmentation pattern, of which 32 were unambiguously identified with reference standards. Furthermore, a practical and feasible method was developed and validated for simultaneous quantification of 18 chemical compounds, of which 17 compounds were steroidal saponins, by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. In addition, it was known that the contents of quantitative compounds varied significantly among multiple Allium chinense samples. Moreover, chemometric analysis results suggested that chinenoside I, macrostemonoside B, and chinenoside II were the most important markers responsible for poor consistency. Taken altogether, this study would be helpful for the chemical authentication and quality control of Allium chinense samples.
语种	英语
出版者	Wiley-VCH Verlag
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266967]
专题	中国科学院上海药物研究所
通讯作者	Yao, Zhihong
作者单位	1.Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; 2.State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, China 3.College of Pharmacy, Jinan University, Guangzhou, China; 4.Guangdong Provincial Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, China; 5.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; 6.School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;
推荐引用方式 GB/T 7714	Qin, Zifei,Lin, Pei,Yao, Zhihong,et al. Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don[J]. Journal of Separation Science,2018,41(23):4253-4271.
APA	Qin, Zifei.,Lin, Pei.,Yao, Zhihong.,Chen, Zilin.,Yu, Yang.,...&Yao, Xinsheng.(2018).Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don.Journal of Separation Science,41(23),4253-4271.
MLA	Qin, Zifei,et al."Diagnostic ion-oriented identification and simultaneous quantification of chemical components in Allium chinense G. Don".Journal of Separation Science 41.23(2018):4253-4271.