Ultrastructural study on the model of human lung adenocarcinoma heterotransplanted to nude mice

	Ultrastructural study on the model of human lung adenocarcinoma heterotransplanted to nude mice
	Dai, Z Q; Zhang, S Y; Xu, J Y; Xu, B
	1987-07
卷号	9
期号	4
页码	248-50
英文摘要	A human lung adenocarcinoma from surgical biopsy specimen was successfully heterotransplanted into nude mice and has been maintained for 40 generations. The experiments were made on 6-8 week old male or female nude mice with Swiss genetic background cultivated in specific pathogen-free condition. The electron microscopic observation on transplanted tumor of passages 2, 6, 12, 18 and 23 revealed that the ultrastructural features of this tumor were strictly maintained and no obvious change of differentiation was found. But there was a potential prone to regional squamous epithelial metaplasia in the transplanted tumor. The nude mice model of human lung adenocarcinoma so established can be used as a good experimental system of the homologous and reproducible human cancer for the study of basic medical sciences and chemotherapy of human lung carcinoma.
会议录	Zhonghua zhong liu za zhi [Chinese journal of oncology]
文献子类	Meeting Abstract;Article
语种	中文
内容类型	会议论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266927]
专题	中国科学院上海药物研究所
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai
推荐引用方式 GB/T 7714	Dai, Z Q,Zhang, S Y,Xu, J Y,et al. Ultrastructural study on the model of human lung adenocarcinoma heterotransplanted to nude mice[C]. 见:.