Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters

doi:10.1186/s12967-015-0629-3

	Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters
	Li, Xiao-Yang 2; Zhao, Zhen-Xiong 2; Huang, Min2 ; Feng, Ru 2; He, Chi-Yu 2; Ma, Chao 3; Luo, Shi-Heng 3; Fu, Jie 2; Wen, Bao-Ying 2; Ren, Long 2
刊名	Journal of translational medicine
	2015-08-27
卷号	13 页码:278
ISSN号	1479-5876
DOI	10.1186/s12967-015-0629-3
文献子类	Article
英文摘要	Berberine (BBR), as a new medicine for hyperlipidemia, can reduce the blood lipids in patients. Mechanistic studies have shown that BBR activates the extracellular-signal regulated kinase pathway by stabilizing low-density-lipoprotein receptor mRNA. However, aside from inhibiting the intestinal absorption of cholesterol, the effects of BBR on other metabolic pathways of cholesterol have not been reported. This study aimed to investigate the action of BBR on the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters.
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266816]
专题	中国科学院上海药物研究所
通讯作者	Li, Xiao-Yang; Zhao, Zhen-Xiong; Huang, Min; Feng, Ru; He, Chi-Yu; Ma, Chao; Luo, Shi-Heng; Fu, Jie; Wen, Bao-Ying; Ren, Long; Shou, Jia-Wen; Guo, Fang; Chen, Yangchao; Gao, Xin; Wang, Yan; Jiang, Jian-Dong
作者单位	1.State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China. jiang 2.State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China; 3.Beijing Analytical Application Center, Shimadzu (China) Co., Ltd., Beijing, 100020, China; 4.School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China; 5.Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China;
推荐引用方式 GB/T 7714	Li, Xiao-Yang,Zhao, Zhen-Xiong,Huang, Min,et al. Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters[J]. Journal of translational medicine,2015,13:278.
APA	Li, Xiao-Yang.,Zhao, Zhen-Xiong.,Huang, Min.,Feng, Ru.,He, Chi-Yu.,...&Jiang, Jian-Dong.(2015).Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters.Journal of translational medicine,13,278.
MLA	Li, Xiao-Yang,et al."Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters".Journal of translational medicine 13(2015):278.