Upconversion-based photodynamic cancer therapy

doi:10.1016/j.ccr.2017.09.006

	Upconversion-based photodynamic cancer therapy
	Liu, Yanyan; Meng, Xianfu; Bu, Wenbo
刊名	COORDINATION CHEMISTRY REVIEWS
	2019-01-15
卷号	379 页码:82
关键词	Photodynamic therapy Upconversion nanoparticles Photosensitizers UCNP-based PDT Synergistic therapy
ISSN号	0010-8545
DOI	10.1016/j.ccr.2017.09.006
文献子类	Review
英文摘要	Photodynamic therapy (PDT) has become widely accepted and utilized for tumor therapy. Considering the natural shortcomings (e.g., lack of an ideal photosensitizer and limited light penetration depth), lanthanide doped upconversion nanoparticles (Ln-doped UCNP), which can be excited with near-infrared light (NIR) for UV/visible/NIR upconversion luminescence (UCL) emissions, show great potential for augmenting biological treatment with PDT for solid tumors and for visual bioimaging of disease lesions. This review summarizes the basic concepts and important influence factors on PDT, the optimized construction of UCNP-based photosensitizer (UCNP-PS) systems, and some representative examples of UCNP-based PDT (UCPDT) applications in combination with other traditional therapy methods, such as chemotherapy, radiotherapy, photothermal therapy (PIT) and gene therapy. This review will provide guidance for the design and fabrication of future new UCNP-based nanocomposites for synergistic UC-PDT therapy. (C) 2017 Elsevier B.V. All rights reserved.
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER SCIENCE SA
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/27396]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Liu, Yanyan,Meng, Xianfu,Bu, Wenbo. Upconversion-based photodynamic cancer therapy[J]. COORDINATION CHEMISTRY REVIEWS,2019,379:82.
APA	Liu, Yanyan,Meng, Xianfu,&Bu, Wenbo.(2019).Upconversion-based photodynamic cancer therapy.COORDINATION CHEMISTRY REVIEWS,379,82.
MLA	Liu, Yanyan,et al."Upconversion-based photodynamic cancer therapy".COORDINATION CHEMISTRY REVIEWS 379(2019):82.