Phosphorylation dependent alpha-synuclein degradation monitored by in-cell NMR

doi:10.1039/c9cc05662a

	Phosphorylation dependent alpha-synuclein degradation monitored by in-cell NMR
	Zheng, Wenwen 1,2; Zhang, Zeting 2; Ye, Yansheng 2; Wu, Qiong 2; Liu, Maili 2; Li, Conggang 2
刊名	CHEMICAL COMMUNICATIONS
	2019-09-25
卷号	55 期号:75 页码:11215-11218
ISSN号	1359-7345
DOI	10.1039/c9cc05662a
英文摘要	Here we report the dephosphorylation and proteolysis of phosphorylated alpha-synuclein, a Parkinson's disease-related protein, in living cells in a time resolved manner using in-cell NMR.
资助项目	Ministry of Science and Technology of China[2017YFA0505400] ; National Natural Sciences Foundation of China[21221064] ; National Natural Sciences Foundation of China[21203243] ; National Natural Sciences Foundation of China[21673284] ; K. C. Wong Education Foundation
WOS关键词	PROTEIN-STRUCTURE DETERMINATION ; SPECTROSCOPY ; TYROSINE ; SER-129 ; SITE
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000486199100010
资助机构	Ministry of Science and Technology of China ; Ministry of Science and Technology of China ; National Natural Sciences Foundation of China ; National Natural Sciences Foundation of China ; K. C. Wong Education Foundation ; K. C. Wong Education Foundation ; Ministry of Science and Technology of China ; Ministry of Science and Technology of China ; National Natural Sciences Foundation of China ; National Natural Sciences Foundation of China ; K. C. Wong Education Foundation ; K. C. Wong Education Foundation ; Ministry of Science and Technology of China ; Ministry of Science and Technology of China ; National Natural Sciences Foundation of China ; National Natural Sciences Foundation of China ; K. C. Wong Education Foundation ; K. C. Wong Education Foundation ; Ministry of Science and Technology of China ; Ministry of Science and Technology of China ; National Natural Sciences Foundation of China ; National Natural Sciences Foundation of China ; K. C. Wong Education Foundation ; K. C. Wong Education Foundation
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/21517]
专题	中国科学院武汉物理与数学研究所
通讯作者	Li, Conggang
作者单位	1.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Key Lab Magnet Resonance Biol Syst,Natl Ctr Magne, Wuhan 430071, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Wenwen,Zhang, Zeting,Ye, Yansheng,et al. Phosphorylation dependent alpha-synuclein degradation monitored by in-cell NMR[J]. CHEMICAL COMMUNICATIONS,2019,55(75):11215-11218.
APA	Zheng, Wenwen,Zhang, Zeting,Ye, Yansheng,Wu, Qiong,Liu, Maili,&Li, Conggang.(2019).Phosphorylation dependent alpha-synuclein degradation monitored by in-cell NMR.CHEMICAL COMMUNICATIONS,55(75),11215-11218.
MLA	Zheng, Wenwen,et al."Phosphorylation dependent alpha-synuclein degradation monitored by in-cell NMR".CHEMICAL COMMUNICATIONS 55.75(2019):11215-11218.