corticalorganizationofcentrifugalafferentstotheolfactorybulbmonoandtranssynaptictracingwithrecombinantneurotropicviraltracers

	corticalorganizationofcentrifugalafferentstotheolfactorybulbmonoandtranssynaptictracingwithrecombinantneurotropicviraltracers
	Wen Pengjie 1; Rao Xiaoping 1; Xu Liuying 2; Zhang Zhijian 1; Jia Fan 1; He Xiaobin 1; Xu Fuqiang 1
刊名	neurosciencebulletin
	2019
卷号	35 期号:4 页码:709
ISSN号	1673-7067
英文摘要	Sensory processing is strongly modulated by different brain and behavioral states, and this is based on the top-down modulation. In the olfactory system, local neural circuits in the olfactory bulb (OB) are innervated by centrifugal afferents in order to regulate the processing of olfactory information in the OB under different behavioral states. The purpose of the present study was to explore the organization of neural networks in olfactory-related cortices and modulatory nuclei that give rise to direct and indirect innervations to the glomerular layer (GL) of the OB at the whole-brain scale. Injection of different recombinant attenuated neurotropic viruses into the GL showed that it received direct inputs from each layer in the OB, centrifugal inputs from the ipsilateralanterior olfactory nucleus (AON), anterior piriform cortex (Pir), and horizontal limb of diagonal band of Broca (HDB), and various indirect inputs from bilateral cortical neurons in the AON, Pir, amygdala, entorhinal cortex, hippocampus, HDB, dorsal raphe, median raphe and locus coeruleus. These results provide a circuitry basis that will help further understand the mechanism by which olfactory informationprocessing in the OB is regulated.
语种	英语
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/19171]
专题	中国科学院武汉物理与数学研究所
作者单位	1.中国科学院武汉物理与数学研究所 2.武汉大学
推荐引用方式 GB/T 7714	Wen Pengjie,Rao Xiaoping,Xu Liuying,et al. corticalorganizationofcentrifugalafferentstotheolfactorybulbmonoandtranssynaptictracingwithrecombinantneurotropicviraltracers[J]. neurosciencebulletin,2019,35(4):709.
APA	Wen Pengjie.,Rao Xiaoping.,Xu Liuying.,Zhang Zhijian.,Jia Fan.,...&Xu Fuqiang.(2019).corticalorganizationofcentrifugalafferentstotheolfactorybulbmonoandtranssynaptictracingwithrecombinantneurotropicviraltracers.neurosciencebulletin,35(4),709.
MLA	Wen Pengjie,et al."corticalorganizationofcentrifugalafferentstotheolfactorybulbmonoandtranssynaptictracingwithrecombinantneurotropicviraltracers".neurosciencebulletin 35.4(2019):709.