Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms

doi:10.1039/c9qo00737g

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms
	Ding, Cai-Feng 2,3; Zhang, Rong-Ping 5,6; Yu, Hao-Fei 1,5,6; Yang, Jing3 ; Qin, Xu-Jie3 ; Dai, Zhi 3; Liu, Ya-Ping 3; Lu, Qiu-Min 4; Lai, Ren 4; Luo, Xiao-Dong1,3
刊名	ORGANIC CHEMISTRY FRONTIERS
	2019-10-07
卷号	6 期号:19 页码:3428-3434
ISSN号	2052-4129
DOI	10.1039/c9qo00737g
通讯作者	Lai, Ren(rlai@mail.kib.ac.cn) ; Luo, Xiao-Dong(xdluo@mail.kib.ac.cn)
英文摘要	Thalfoetines A-D (1-4), unique hybrid aporphine alkaloids with a C-7 aromatic unit formed by a new C-C bond linking two building blocks, were isolated from Thalictrum foetidum. Their structures were elucidated by extensive spectroscopic and computational analysis. They inhibited bacteria significantly, and compound 1 damaged the cell structure of Staphylococcus aureus and inhibited its DNA synthesis.
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000487508600017
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/69470]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Lai, Ren; Luo, Xiao-Dong
作者单位	1.Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ & Yunnan Prov, Kunming 650091, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Key Lab Phytochem & Plant Resources West China, Kunming 650201, Yunnan, Peoples R China 4.Chinese Acad Sci & Yunnan Prov, Key Lab Anim Models & Human Dis Mech, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China 5.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China 6.Kunming Med Univ, Yunnan Key Lab Pharmacologyf Nat Prod, Kunming 650500, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Ding, Cai-Feng,Zhang, Rong-Ping,Yu, Hao-Fei,et al. Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(19):3428-3434.
APA	Ding, Cai-Feng.,Zhang, Rong-Ping.,Yu, Hao-Fei.,Yang, Jing.,Qin, Xu-Jie.,...&Luo, Xiao-Dong.(2019).Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms.ORGANIC CHEMISTRY FRONTIERS,6(19),3428-3434.
MLA	Ding, Cai-Feng,et al."Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms".ORGANIC CHEMISTRY FRONTIERS 6.19(2019):3428-3434.