Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects

doi:10.1016/j.phytochem.2019.112065

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects
	Fan, Min1,2 ; Luo, Dan 1; Peng, Li-Yan 1; Li, Xiao-Nian 1; Wu, Xing-De 1; Ji, Xu1 ; Zhao, Qin-Shi1
刊名	PHYTOCHEMISTRY
	2019-10-01
卷号	166 页码:11
关键词	Salvia hispanica L. (Lamiaceae) Chia Neo-clerodane diterpenoids Hispanins A-J Single crystal X-ray diffraction analysis Cardioprotective effects
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2019.112065
通讯作者	Wu, Xing-De(wuxingde@mail.kib.ac.cn) ; Ji, Xu(jixu@mail.kib.ac.cn) ; Zhao, Qin-Shi(qinshizhao@mail.kib.ac.cn)
英文摘要	Ten undescribed neo-clerodane diterpenoids, named hispanins A-J, together with six known ones, were isolated from the aerial parts of Salvia hispanica L. Their structures were established by extensive spectroscopic analysis. The absolute configurations of the undescribed compounds were determined by the ECD data and single crystal X-ray diffraction analysis. Hispanins B and C represented the first neo-clerodane diterpenoids with a unique oxygen bridge between C-19 and C-20. All isolated compounds were evaluated for their protective effects against H2O2-induced cardiomyocyte injury. Five of these compounds showed significant cardioprotective effects.
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
WOS记录号	WOS:000484650500014
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/68629]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Wu, Xing-De; Ji, Xu; Zhao, Qin-Shi
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China 2.Dali Univ, Coll Pharmaceut Sci, Dali 671000, Peoples R China
推荐引用方式 GB/T 7714	Fan, Min,Luo, Dan,Peng, Li-Yan,et al. Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects[J]. PHYTOCHEMISTRY,2019,166:11.
APA	Fan, Min.,Luo, Dan.,Peng, Li-Yan.,Li, Xiao-Nian.,Wu, Xing-De.,...&Zhao, Qin-Shi.(2019).Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects.PHYTOCHEMISTRY,166,11.
MLA	Fan, Min,et al."Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects".PHYTOCHEMISTRY 166(2019):11.