Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta. | |
Zuyue Chen1,2; Lauri Parkkonen1; Jingkuan We3; Jin-Run Dong3; Yuanye Ma3; Synnove Carlson1,2 | |
刊名 | Neurosci.Bull. |
2018 | |
卷号 | 34期号:2页码:291-302 |
关键词 | Prepulse Inhibition Superior Temporal Gyrus Local Field Potential |
DOI | 10.1007/s12264-017-0181-7 |
英文摘要 | Prepulse inhibition (PPI) refers to a decreasedresponse to a startling stimulus when another weakerstimulus precedes it. Most PPI studies have focused on thephysiological startle reflex and fewer have reported the PPIof cortical responses. We recorded local field potentials(LFPs) in four monkeys and investigated whether the PPIof auditory cortical responses (alpha, beta, and gammaoscillations and evoked potentials) can be demonstrated inthe caudolateral belt of the superior temporal gyrus(STGcb). We also investigated whether the presence of aconspecific, which draws attention away from the auditorystimuli, affects the PPI of auditory cortical responses. ThePPI paradigm consisted of Pulse-only and Pre-pulse ? Pulse trials that were presented randomly whilethe monkey was alone (ALONE) and while anothermonkey was present in the same room (ACCOMP). TheLFPs to the Pulse were significantly suppressed by thePrepulse thus, demonstrating PPI of cortical responses inthe STGcb. The PPI-related inhibition of the N1 amplitudeof the evoked responses and cortical oscillations to thePulse were not affected by the presence of a conspecific. Incontrast, gamma oscillations and the amplitude of the N1response to Pulse-only were suppressed in the ACCOMPcondition compared to the ALONE condition. Thesefindings demonstrate PPI in the monkey STGcb andsuggest that the PPI of auditory cortical responses in themonkey STGcb is a pre-attentive inhibitory process that isindependent of attentional modulation. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://159.226.149.26:8080/handle/152453/12233] |
专题 | 灵长类研究中心 |
通讯作者 | Zuyue Chen |
作者单位 | 1.Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, 00076 Espoo, Finland 2.Department of Physiology, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland 3.Laboratory of Primate Neurosciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China |
推荐引用方式 GB/T 7714 | Zuyue Chen,Lauri Parkkonen,Jingkuan We,et al. Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta.[J]. Neurosci.Bull.,2018,34(2):291-302. |
APA | Zuyue Chen,Lauri Parkkonen,Jingkuan We,Jin-Run Dong,Yuanye Ma,&Synnove Carlson.(2018).Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta..Neurosci.Bull.,34(2),291-302. |
MLA | Zuyue Chen,et al."Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta.".Neurosci.Bull. 34.2(2018):291-302. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论