Rh(I)/DpenPhos catalyzed asymmetric hydrogenation of enol esters and potassium (E)-3-cyano-5-methylhex-3-enoate

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	Rh(I)/DpenPhos catalyzed asymmetric hydrogenation of enol esters and potassium (E)-3-cyano-5-methylhex-3-enoate
	Liu Y(刘龑) ; Wang Z(王正) ; Ding KL(丁奎岭)
刊名	Tetrahedron
	2012
卷号	68 期号:37 页码:7581-7585
ISSN号	0040-4020
其他题名	Rh/DpenPhos催化烯醇酯以及(E)-3-氰基-5-甲基-3-己烯酸钾盐的不对称氢化
通讯作者	丁奎岭
英文摘要	Rh(I) complexes of a class of modular chiral monodentate phosphoramidites were highly efficient for the asymmetric hydrogenation of enol esters bearing alpha-aryl or alpha-alkyl groups, to afford the corresponding hydrogenation products in high enantioselectivities (87-95% ee) and reactivities (turnover number up to 10,000). These ligands were also shown to be effective in Rh(I)-catalyzed asymmetric hydrogenation of the potassium salt of (E)-3-cyano-5-methylhex-3-enoate, to give the corresponding product (a precursor to CI-1008) with up to 95% ee and complete conversion of substrate. (C) 2012 Elsevier Ltd. All rights reserved.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tet.2012.05.096
语种	英语
WOS记录号	WOS:000307802300008
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28097]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Liu Y,Wang Z,Ding KL. Rh(I)/DpenPhos catalyzed asymmetric hydrogenation of enol esters and potassium (E)-3-cyano-5-methylhex-3-enoate[J]. Tetrahedron,2012,68(37):7581-7585.
APA	刘龑,王正,&丁奎岭.(2012).Rh(I)/DpenPhos catalyzed asymmetric hydrogenation of enol esters and potassium (E)-3-cyano-5-methylhex-3-enoate.Tetrahedron,68(37),7581-7585.
MLA	刘龑,et al."Rh(I)/DpenPhos catalyzed asymmetric hydrogenation of enol esters and potassium (E)-3-cyano-5-methylhex-3-enoate".Tetrahedron 68.37(2012):7581-7585.