Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies

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	Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies
	Liu WB(刘文博) ; Zheng C(郑超) ; Zhuo CX(卓春祥) ; Dai LX(戴立信) ; You SL(游书力)
刊名	J. Am. Chem. Soc.
	2012
卷号	134 期号:10 页码:4812-4821
ISSN号	0002-7863
其他题名	N-芳基膦氮配体参与的铱催化的不对称烯丙基烷基化反应: 范围与机理研究
通讯作者	游书力
英文摘要	A series of N-aryl phosphoramidite ligands has been synthesized and applied to iridium-catalyzed allylic alkylation reactions, offering high regio- and enantioselectivities for a wide variety of substrates. These ligands feature the synthetic convenience and good tolerance of the ortho-substituted cinnamyl carbonates. Mechanistic studies, including DFT calculations and X-ray crystallographic analyses of the (pi-allyl)-Ir complexes, reveal that the active iridacycle is formed via C(sp(2))-H bond activation.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ja210923k
语种	英语
WOS记录号	WOS:000301990600057
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28011]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Liu WB,Zheng C,Zhuo CX,et al. Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies[J]. J. Am. Chem. Soc.,2012,134(10):4812-4821.
APA	刘文博,郑超,卓春祥,戴立信,&游书力.(2012).Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies.J. Am. Chem. Soc.,134(10),4812-4821.
MLA	刘文博,et al."Iridium-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies".J. Am. Chem. Soc. 134.10(2012):4812-4821.