Efficient Synthesis of 4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides from 1,2-Allenylphosphonates and CuX2 and Subsequent Suzuki Cross-Coupling of the C-Cl Bonds

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	Efficient Synthesis of 4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides from 1,2-Allenylphosphonates and CuX2 and Subsequent Suzuki Cross-Coupling of the C-Cl Bonds
	Xin N(辛宁) ; Ma SM(麻生明)
刊名	Eur. J. Org. Chem.
	2012
期号	20 页码:3806-3817
ISSN号	1434-193X
其他题名	从1,2-炔基膦和CuX2出发和成4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides的方法, 以及C-Cl键的Suzuki偶联反应
通讯作者	麻生明
英文摘要	A convenient and efficient synthesis of 4-halo-2,5-dihydro-1,2-oxaphosphole 2-oxides through CuX2-mediated direct halocyclization of diethyl 1,2-allenylphosphonates was developed. The yields range from moderate to excellent. The efficiency of axial-to-central chirality transfer has also been studied. Further Suzuki cross-coupling of the resulting vinylic chlorides with dicyclohexyl(2,4,6-trimethoxyphenyl)phosphane (LB-Phos) as the ligand, was established.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/ejoc.201200228
语种	英语
WOS记录号	WOS:000305942800012
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/27943]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Xin N,Ma SM. Efficient Synthesis of 4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides from 1,2-Allenylphosphonates and CuX2 and Subsequent Suzuki Cross-Coupling of the C-Cl Bonds[J]. Eur. J. Org. Chem.,2012(20):3806-3817.
APA	辛宁,&麻生明.(2012).Efficient Synthesis of 4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides from 1,2-Allenylphosphonates and CuX2 and Subsequent Suzuki Cross-Coupling of the C-Cl Bonds.Eur. J. Org. Chem.(20),3806-3817.
MLA	辛宁,et al."Efficient Synthesis of 4-Halo-2,5-dihydro-1,2-oxaphosphole 2-Oxides from 1,2-Allenylphosphonates and CuX2 and Subsequent Suzuki Cross-Coupling of the C-Cl Bonds".Eur. J. Org. Chem. .20(2012):3806-3817.