Traceless-Activation Strategy for Rh-Catalyzed Csp(2)-H Arylation of Coumarins

doi:10.1021/acs.orglett.9b02040

	Traceless-Activation Strategy for Rh-Catalyzed Csp(2)-H Arylation of Coumarins
	Han, Fuzhong 1; Xun, Shanshan 1; Jia, Lina 1; Zhang, Yutong 1; Zou, Liwei 2; Hu, Xiangping 2
刊名	ORGANIC LETTERS
	2019-08-02
卷号	21 期号:15 页码:5907-5911
ISSN号	1523-7060
DOI	10.1021/acs.orglett.9b02040
通讯作者	Han, Fuzhong(hanfuzhongchn@163.com) ; Hu, Xiangping(xiangping@dicp.ac.cn)
英文摘要	A traceless-activation strategy for the synthesis of 4-arylchroman-2-ones via a Rh(III)-catalyzed C-H activation of 2-arylpyridines and subsequent conjugated/decarboxylative addition to coumarin-3-carboxylic acids has been reported. The carboxyl group at C3 position of coumarin proved to be crucial to realize the reaction, which is spontaneously removed after the reaction by the release of CO2. The reaction displayed good substrate tolerance and gave various 4-arylchroman-2-ones in up to 90% yield.
资助项目	University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province[2016204]
WOS关键词	C-H ACTIVATION ; COMPLEX FLAVONOIDS ; FARINOSE EXUDATE ; BOND FORMATION ; ENANTIOSELECTIVE SYNTHESIS ; BIOLOGICAL EVALUATION ; FACILE SYNTHESIS ; ACIDS ; CYCLIZATION ; ANNULATION
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000480371600029
资助机构	University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province ; University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/173596]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Han, Fuzhong; Hu, Xiangping
作者单位	1.Qiqihar Univ, Coll Chem & Chem Engn, Qiqihar 161006, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, 457 Zhongshan Rd, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Han, Fuzhong,Xun, Shanshan,Jia, Lina,et al. Traceless-Activation Strategy for Rh-Catalyzed Csp(2)-H Arylation of Coumarins[J]. ORGANIC LETTERS,2019,21(15):5907-5911.
APA	Han, Fuzhong,Xun, Shanshan,Jia, Lina,Zhang, Yutong,Zou, Liwei,&Hu, Xiangping.(2019).Traceless-Activation Strategy for Rh-Catalyzed Csp(2)-H Arylation of Coumarins.ORGANIC LETTERS,21(15),5907-5911.
MLA	Han, Fuzhong,et al."Traceless-Activation Strategy for Rh-Catalyzed Csp(2)-H Arylation of Coumarins".ORGANIC LETTERS 21.15(2019):5907-5911.