Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols

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	Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols
	Zhou QZ ; Yang YN ; Chen ZK ; Sun A
刊名	chemistry and physics of lipids
	1998
卷号	95 期号:1 页码:1-9
关键词	olfactory sensor interdigital electrode hydrocarbon chain head-group voltage response LIPOSOMES ODORANTS PACKING SENSOR LIPID-MEMBRANES
ISSN号	0009-3084
通讯作者	zhou qz,peking univ,coll chem & mol engn,beijing 100871,peoples r china.
中文摘要	in order to understand the relationship between phospholipid molecular structures and their olfactory responses to odorants, we designed and synthesized four phosphatidylcholine analogues with different long hydrocarbon (ch) chains and selected three natural phospholipids with different head-groups. by using interdigital electrodes (ies) as olfactory sensors (oss), we measured the responses of the ifs coated with these seven different lipid membranes to four alcohol vapors in a gas flow system. the ifs voltage changes were recorded and the voltage-relative saturate vapor pressure (v-p/p degrees) curves were also plotted. it was found that with a methyl (-ch3) placed at the c-8 position in the 18-carbon chain, the olfactory responses could be improved about ten times and with conjugated double bonds (c=c) in the long chains, the sensitivity could be increased by 3 similar to 4 orders of magnitude. as to head-groups, choline is preferred over ethanolamine and serine in phospholipid structures in terms of high olfactory sensitivity: these results are expected to be useful in further designing and manufacturing lipid-mimicking oss. (c) 1998 elsevier science ireland ltd. all rights reserved.
学科主题	半导体器件
收录类别	SCI
语种	英语
公开日期	2010-08-12
内容类型	期刊论文
源URL	[http://ir.semi.ac.cn/handle/172111/13080]
专题	半导体研究所_中国科学院半导体研究所（2009年前）
推荐引用方式 GB/T 7714	Zhou QZ,Yang YN,Chen ZK,et al. Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols[J]. chemistry and physics of lipids,1998,95(1):1-9.
APA	Zhou QZ,Yang YN,Chen ZK,&Sun A.(1998).Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols.chemistry and physics of lipids,95(1),1-9.
MLA	Zhou QZ,et al."Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols".chemistry and physics of lipids 95.1(1998):1-9.