Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry
	Yang, Wei 1; Fang, Dong-Mei 2; He, Hong-Ping 1; Hao, Xiao-Jiang1 ; Wu, Zhi-Jun 2; Zhang, Guo-Lin 2
刊名	RAPID COMMUNICATIONS IN MASS SPECTROMETRY
	2013-06-15
卷号	27 期号:11 页码:1203-1212
关键词	CIPADESSA-CINERASCENS CITRUS LIMONOIDS SANDORICUM-KOETJAPE PHENOLIC-COMPOUNDS LIMONIN GLUCOSIDE IONIZATION LEAVES TETRANORTRITERPENOIDS INHIBITION EXTRACTS
ISSN号	0951-4198
通讯作者	He, HP (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China. ; hehongping@mail.kib.ac.cn ; wuzj@cib.ac.cn
英文摘要	RATIONALE Limonoids, a class of tetranortriterpenoids, exhibit various biological effects, including acting as potent antifeedants and insect growth-regulators against various pests. The analysis of phragmalin- and mexicanolide-type limonoids by collision-induced dissociation tandem mass spectrometry (CID-MS/MS) has not been reported. METHODS A high-performance liquid chromatography/electrospray ionization (HPLC/ESI)-MS/MS method was developed to investigate the fragmentation patterns of [M+NH4]+ ions for nine reference phragmalin- and mexicanolide-type limonoids. The method was also used in the identification of limonoid compounds in botanic extracts of Heynea trijuga. RESULTS The losses of side chains and the furan part were the major fragmentation patterns. However, there was variation in the relative abundances of product ions resulting from the same fragmentation pathways. A total of 89 phragmalin- and mexicanolide-type limonoids in botanic extracts of Heynea trijuga were detected and 50 of these compounds were identified or tentatively characterized based on elemental constituents, fragmentation pathways, and the profile of the major product ions of reference compounds. In addition, the isomers could be tentatively distinguished. CONCLUSIONS An HPLC/ESI-MS/MS method was developed and could be used to simultaneously identify and screen phragmalin- and mexicanolide-type limonoids in botanic extracts of Heynea trijuga. Copyright (c) 2013 John Wiley & Sons, Ltd.
学科主题	Biochemistry & Molecular Biology; Chemistry; Spectroscopy
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]	Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
关键词[WOS]	CIPADESSA-CINERASCENS ; CITRUS LIMONOIDS ; SANDORICUM-KOETJAPE ; PHENOLIC-COMPOUNDS ; LIMONIN GLUCOSIDE ; IONIZATION ; LEAVES ; TETRANORTRITERPENOIDS ; INHIBITION ; EXTRACTS
收录类别	SCI
资助信息	West Light Foundation of the Chinese Academy of Sciences [Y2C6031100]; National Natural Science Foundation of China [20932007, 21172214]; Yong Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
语种	英语
WOS记录号	WOS:000318626500004
公开日期	2013-06-08
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/16461]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China
推荐引用方式 GB/T 7714	Yang, Wei,Fang, Dong-Mei,He, Hong-Ping,et al. Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2013,27(11):1203-1212.
APA	Yang, Wei,Fang, Dong-Mei,He, Hong-Ping,Hao, Xiao-Jiang,Wu, Zhi-Jun,&Zhang, Guo-Lin.(2013).Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,27(11),1203-1212.
MLA	Yang, Wei,et al."Analysis of mexicanolide- and phragmalin-type limonoids from Heynea trijuga using high-performance liquid chromatography/electrospray tandem mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 27.11(2013):1203-1212.