Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics
	Wu, Huifeng1,2 ; Liu, Xiaoli 1,2,3; Zhao, Jianmin1,2 ; Yu, Junbao1,2 ; Pang, Qiuying 4,5; Feng, Jianghua
刊名	ECOTOXICOLOGY
	2012-11-01
卷号	21 期号:8 页码:2363-2371
关键词	Metal Toxicology Halophyte NMR Metabolite
ISSN号	0963-9292
通讯作者	Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China.,hfwu@yic.ac.cn
产权排序	[Wu, Huifeng; Liu, Xiaoli; Zhao, Jianmin; Yu, Junbao] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China; [Wu, Huifeng; Liu, Xiaoli; Zhao, Jianmin; Yu, Junbao] YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Shandong, Peoples R China; [Liu, Xiaoli] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China; [Pang, Qiuying] NE Forestry Univ, Alkali Soil Nat Environm Sci Ctr, Harbin 150040, Heilongjiang, Peoples R China; [Pang, Qiuying] Minist Educ, Key Lab Saline Alkali Vegetat Ecol Restorat Oil F, Harbin 150040, Heilongjiang, Peoples R China
中文摘要	Lead (Pb) and zinc (Zn) are two typical metal contaminants with high levels in both seawater and sediment in the intertidal zones of the Bohai Sea. Suaeda salsa is the pioneer halophyte plant in the intertidal zones of the Bohai Sea. In the present work, the short (1 week) and long term (1 month) toxicological effects of environmentally relevant concentrations of Pb and Zn were characterized in S. salsa using NMR-based metabolomics combined with antioxidant enzyme activities. After metal exposure for 1 week, no significant metabolic responses were detected in root tissues of S. salsa. The significant metabolic responses included the increase of isocaproate, glucose and fructose, and decrease of malate, citrate and sucrose in root tissues of S. salsa exposed to Pb for 1 month. The increased phosphocholine and betaine, and decreased choline were uniquely found in Zn-exposed samples. The metabolic changes including decreased malate, citrate and sucrose were detected in both Pb and Zn-exposed groups. These metabolic biomarkers revealed that both Pb and Zn exposures could induce osmotic stress and disturbances in energy metabolism in S. salsa after exposures for 1 month. Overall, this work demonstrates that metabolomics can be used to elucidate toxicological effects of environmentally relevant metal contaminants using halophyte S. salsa as the bioindicator.
英文摘要	Lead (Pb) and zinc (Zn) are two typical metal contaminants with high levels in both seawater and sediment in the intertidal zones of the Bohai Sea. Suaeda salsa is the pioneer halophyte plant in the intertidal zones of the Bohai Sea. In the present work, the short (1 week) and long term (1 month) toxicological effects of environmentally relevant concentrations of Pb and Zn were characterized in S. salsa using NMR-based metabolomics combined with antioxidant enzyme activities. After metal exposure for 1 week, no significant metabolic responses were detected in root tissues of S. salsa. The significant metabolic responses included the increase of isocaproate, glucose and fructose, and decrease of malate, citrate and sucrose in root tissues of S. salsa exposed to Pb for 1 month. The increased phosphocholine and betaine, and decreased choline were uniquely found in Zn-exposed samples. The metabolic changes including decreased malate, citrate and sucrose were detected in both Pb and Zn-exposed groups. These metabolic biomarkers revealed that both Pb and Zn exposures could induce osmotic stress and disturbances in energy metabolism in S. salsa after exposures for 1 month. Overall, this work demonstrates that metabolomics can be used to elucidate toxicological effects of environmentally relevant metal contaminants using halophyte S. salsa as the bioindicator.
学科主题	Ecology; Environmental Sciences; Toxicology
研究领域[WOS]	Environmental Sciences & Ecology ; Toxicology
关键词[WOS]	V-H+-ATPASE ; CADMIUM EXPOSURE ; ACCUMULATION ; SPECTROSCOPY ; EXPRESSION ; RESPONSES ; TOXICITY ; STRESS ; LEAVES ; PLANTS
收录类别	SCI
资助信息	National Science & Technology Pillar Program [2011BAC02B01]; Chinese Academy of Sciences
原文出处	http://dx.doi.org/10.1007/s10646-012-0992-2
语种	英语
WOS记录号	WOS:000312664900026
公开日期	2013-03-08
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/6067]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_滨海湿地实验室烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China 2.YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Shandong, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 4.NE Forestry Univ, Alkali Soil Nat Environm Sci Ctr, Harbin 150040, Heilongjiang, Peoples R China 5.Minist Educ, Key Lab Saline Alkali Vegetat Ecol Restorat Oil F, Harbin 150040, Heilongjiang, Peoples R China
推荐引用方式 GB/T 7714	Wu, Huifeng,Liu, Xiaoli,Zhao, Jianmin,et al. Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics[J]. ECOTOXICOLOGY,2012,21(8):2363-2371.
APA	Wu, Huifeng,Liu, Xiaoli,Zhao, Jianmin,Yu, Junbao,Pang, Qiuying,&Feng, Jianghua.(2012).Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics.ECOTOXICOLOGY,21(8),2363-2371.
MLA	Wu, Huifeng,et al."Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics".ECOTOXICOLOGY 21.8(2012):2363-2371.