Self-supported heterogeneous titanium catalysts for enantioselective carbonyl-ene and sulfoxidation reactions

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	Self-supported heterogeneous titanium catalysts for enantioselective carbonyl-ene and sulfoxidation reactions
	Wang XS(王细胜) ; Wang XW(王兴旺) ; Guo HC(郭红超) ; Wang Z(王正) ; Ding KL(丁奎岭)
刊名	Chem.-Eur. J.
	2005
卷号	11 期号:14 页码:4078-4088
ISSN号	0947-6539
其他题名	自负载的非均相Ti催化剂用于不对称羰基-烯和硫醚氧化反应
通讯作者	丁奎岭
英文摘要	A new strategy for the heterogenization of chiral titanium complexes was developed by the in situ assembly of bridged multitopic BINOL ligands with [Ti(OiPr)(4)] without using a support. The assembled heterogeneous catalysts (self-supported) showed excellent enantioselectivity in both the carbonyl-ene reaction of alpha-methylstyrene with ethyl glyoxylate (up to 98% ee) and the oxidation of sulfides (up to > 99% ee). The catalytic performance of these heterogeneous catalytic systems was comparable or even superior to that attained with their homogeneous counterparts. The spacers between the two BINOL units of the ligands in the assembled catalysts had significant impact on the enantioselectivity of the carbonyl-ene reaction. This demonstrates the importance of the supramolecular structures of the assemblies on their catalytic behavior. In the catalysis of sulfoxidation, the self-supported heterogeneous titanium catalysts were highly stable and could be readily recycled and reused for over one month (at least eight cycles) without significant loss of activity and enantioselectivity (up to > 99.9% ee). The features of these self-supported catalysts, such as facile preparation, robust chiral structure of solid-state catalysts, high density of the catalytically active units in the solids, as well as easy recovery and simple recycling, are particularly important in developing methods for the synthesis of optically active compounds in industrial processes.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/chem.200500239
语种	英语
WOS记录号	WOS:000230380300003
公开日期	2013-02-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/17799]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Wang XS,Wang XW,Guo HC,et al. Self-supported heterogeneous titanium catalysts for enantioselective carbonyl-ene and sulfoxidation reactions[J]. Chem.-Eur. J.,2005,11(14):4078-4088.
APA	王细胜,王兴旺,郭红超,王正,&丁奎岭.(2005).Self-supported heterogeneous titanium catalysts for enantioselective carbonyl-ene and sulfoxidation reactions.Chem.-Eur. J.,11(14),4078-4088.
MLA	王细胜,et al."Self-supported heterogeneous titanium catalysts for enantioselective carbonyl-ene and sulfoxidation reactions".Chem.-Eur. J. 11.14(2005):4078-4088.