Fluorine-Containing Furan Derivatives from the Michael Addition of Ethyl 4,4,4-Trifluoro-3-oxobutanoate with beta-Nitrostyrenes

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	Fluorine-Containing Furan Derivatives from the Michael Addition of Ethyl 4,4,4-Trifluoro-3-oxobutanoate with beta-Nitrostyrenes
	Song LP(宋力平) ; Li XF(李宪甫) ; Xing CH(邢春晖) ; Li DM(李冬梅) ; Zhu SZ(朱仕正) ; Deng HM(邓红梅) ; Shao M(邵敏)
刊名	Synlett
	2010
期号	5 页码:830-834
ISSN号	0936-5214
其他题名	三氟乙酰乙酸乙酯与β-硝基苯乙烯的Michael加成反应制备含氟呋喃衍生物
通讯作者	宋力平 ; 朱仕正
英文摘要	Ethyl 4,4,4-trifluoro-3-oxobutanoate reacted with nitrostyrenes in the presence of Et3N to afford ethyl 5-(hydroxyimino)- 4-aryl-2-(trifluoromethyl)-2,5-dihydrofuran-3-carboxylates along with a small amount of ethyl 2-hydroxy-5-imino-4-aryl-2-(trifluoromethyl)- 2,5-dihydrofuran-3-carboxylates. Treatment of ethyl 5( hydroxyimino)-4-aryl-2-(trifluoromethyl)-2,5-dihydrofuran-3-carboxylates with 1.2 equivalents of TsOH in t-BuOH, afforded ethyl 2-hydroxy-5-imino-4-aryl-2-(trifluoromethyl)-2,5-dihydrofuran-3-carboxyl ates in good yields. However, ethyl 2-ethoxy or methoxy-5-oxo-4-aryl-2-(trifluoromethyl)-2,5-dihydrofuran-3-carboxylates were obtained as major products in EtOH or MeOH along with a small amount of ethyl 2-hydroxy-5-imino-4-aryl-2-(trifluoromethyl)- 2,5-dihydrofuran-3-carboxylates.
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1055/s-0029-1219199
语种	英语
WOS记录号	WOS:000275848600033
公开日期	2013-01-18
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14494]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Song LP,Li XF,Xing CH,et al. Fluorine-Containing Furan Derivatives from the Michael Addition of Ethyl 4,4,4-Trifluoro-3-oxobutanoate with beta-Nitrostyrenes[J]. Synlett,2010(5):830-834.
APA	宋力平.,李宪甫.,邢春晖.,李冬梅.,朱仕正.,...&邵敏.(2010).Fluorine-Containing Furan Derivatives from the Michael Addition of Ethyl 4,4,4-Trifluoro-3-oxobutanoate with beta-Nitrostyrenes.Synlett(5),830-834.
MLA	宋力平,et al."Fluorine-Containing Furan Derivatives from the Michael Addition of Ethyl 4,4,4-Trifluoro-3-oxobutanoate with beta-Nitrostyrenes".Synlett .5(2010):830-834.