Highly enantio- and diastereoselective synthesis of alpha-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

CORC > 上海有机化学研究所 > 中国科学院上海有机化学研究所 > 中科院有机氟化学重点实验室

	Highly enantio- and diastereoselective synthesis of alpha-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst
	Li P(李鹏) ; Chai Z(柴卓) ; Zhao SL(赵胜利) ; Yang YQ(杨映全) ; Wang HF(王海峰) ; Zheng CW(郑昌武) ; Cai YP(蔡跃鹏) ; Zhao G(赵刚) ; Zhu SZ(朱仕正)
刊名	Chem. Commun.
	2009
期号	47 页码:7369-7371
ISSN号	1359-7345
其他题名	硫脲催化剂催化氰基乙酮和三氟甲基不饱和酮对映选择性合成a-三氟甲基吡喃
通讯作者	赵刚 ; 朱仕正
英文摘要	The first enantioselective Michael addition of alpha-cyanoketones to alpha,beta-unsaturated trifluoromethyl ketones using a novel piperazine-thiourea catalyst was described. The resulting alpha-trifluoromethyldihydropyrans were obtained in high yields and with up to 95% ee within a short reaction time. A useful transformation of the chiral adduct was also illustrated.
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1039/b915210e
语种	英语
WOS记录号	WOS:000272106200030
公开日期	2013-01-18
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14456]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Li P,Chai Z,Zhao SL,et al. Highly enantio- and diastereoselective synthesis of alpha-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst[J]. Chem. Commun.,2009(47):7369-7371.
APA	李鹏.,柴卓.,赵胜利.,杨映全.,王海峰.,...&朱仕正.(2009).Highly enantio- and diastereoselective synthesis of alpha-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst.Chem. Commun.(47),7369-7371.
MLA	李鹏,et al."Highly enantio- and diastereoselective synthesis of alpha-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst".Chem. Commun. .47(2009):7369-7371.