Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13

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	Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13
	Li WL(李文玲) ; Yi YH(易杨华) ; Wu HM(吴厚铭) ; Xu QZ(徐强芝) ; Tang HF(唐海峰) ; Lin HW(林厚文) ; Wang ZH(王中华)
刊名	J. Nat. Prod.
	2003
卷号	66 期号:1 页码:146-148
ISSN号	0163-3864
其他题名	细胞毒素环七肽 phakellistatin 13的分离和结构
通讯作者	易杨华
中文摘要	A new cyclic hepptapeptide phakellistatin 13(1) had been isolated from the sponge phakellia fusca Thiele, collected at Yongxing Island of China. Its structure was elucidated as cyclo-(Pro~1Trp_leu-Thr-Pro~2-Gly-Phe) on the basis of MS, UV, IR, and high-field NMR (600 MHz) analysis. The compound was significantly cytotoxic against the human hepatoma BEL-7404 cell line with an ED^50<10-2 μg/mL
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/np020223y
语种	英语
WOS记录号	WOS:000180623400033
公开日期	2013-02-21
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/17319]
专题	上海有机化学研究所_上海有机化学研究所
推荐引用方式 GB/T 7714	Li WL,Yi YH,Wu HM,et al. Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13[J]. J. Nat. Prod.,2003,66(1):146-148.
APA	李文玲.,易杨华.,吴厚铭.,徐强芝.,唐海峰.,...&王中华.(2003).Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13.J. Nat. Prod.,66(1),146-148.
MLA	李文玲,et al."Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13".J. Nat. Prod. 66.1(2003):146-148.