NONCODE 2016: an informative and valuable data source of long non-coding RNAs
Zhao, Yi1,2; Li, Hui3,4; Fang, Shuangsang3,4; Kang, Yue4,5; Wu, Wei4,5; Hao, Yajing4,5; Li, Ziyang3; Bu, Dechao3; Sun, Ninghui3; Zhang, Michael Q.1,2
刊名NUCLEIC ACIDS RESEARCH
2016-01-04
卷号44期号:D1页码:D203-D208
ISSN号0305-1048
DOI10.1093/nar/gkv1252
英文摘要NONCODE (http://www.bioinfo.org/noncode/) is an interactive database that aims to present the most complete collection and annotation of non-coding RNAs, especially long non-coding RNAs (lncRNAs). The recently reduced cost of RNA sequencing has produced an explosion of newly identified data. Revolutionary third-generation sequencing methods have also contributed to more accurate annotations. Accumulative experimental data also provides more comprehensive knowledge of lncRNA functions. In this update, NONCODE has added six new species, bringing the total to 16 species altogether. The lncRNAs in NONCODE have increased from 210 831 to 527,336. For human and mouse, the lncRNA numbers are 167,150 and 130,558, respectively. NONCODE 2016 has also introduced three important new features: (i) conservation annotation; (ii) the relationships between lncRNAs and diseases; and (iii) an interface to choose high-quality datasets through predicted scores, literature support and long-read sequencing method support. NONCODE is also accessible through http://www.noncode.org/.
资助项目National High Technology Research and Development Program ('863' Program) of China[2014AA021103] ; National High Technology Research and Development Program ('863' Program) of China[2014AA021502] ; National Natural Science Foundation of China[91229120] ; National Natural Science Foundation of China[31371320] ; National Natural Science Foundation of China[31401119] ; Chinese Academy of Science Strategic Project of Leading Science and Technology[XDA01020402]
WOS研究方向Biochemistry & Molecular Biology
语种英语
出版者OXFORD UNIV PRESS
WOS记录号WOS:000371261700027
内容类型期刊论文
源URL[http://119.78.100.204/handle/2XEOYT63/8617]  
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Zhang, Michael Q.; Chen, Runsheng
作者单位1.Tsinghua Univ, Sch Med, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China
2.Tsinghua Univ, Bioinformat Div, Ctr Synthet & Syst Biol, TNLIST Dept Automat, Beijing 100084, Peoples R China
3.Chinese Acad Sci, Key Lab Intelligent Informat Proc, Adv Comp Res Ctr, State Key Lab Comp Architecture,Inst Comp Technol, Beijing 100190, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
5.Chinese Acad Sci, Inst Biophys, CAS Key Lab RNA Biol, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Yi,Li, Hui,Fang, Shuangsang,et al. NONCODE 2016: an informative and valuable data source of long non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2016,44(D1):D203-D208.
APA Zhao, Yi.,Li, Hui.,Fang, Shuangsang.,Kang, Yue.,Wu, Wei.,...&Chen, Runsheng.(2016).NONCODE 2016: an informative and valuable data source of long non-coding RNAs.NUCLEIC ACIDS RESEARCH,44(D1),D203-D208.
MLA Zhao, Yi,et al."NONCODE 2016: an informative and valuable data source of long non-coding RNAs".NUCLEIC ACIDS RESEARCH 44.D1(2016):D203-D208.
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