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	Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters
	Chen, Hao1,2; He, Maomao1,2; Wang, Yaya1,2; Zhai, Linhui1,2; Cui, Yongbo1,2; Li, Yangyan1,2; Li, Yan3; Zhou, Haibing1,2; Hong, Xuechuan1,2; Deng, Zixin1,2
刊名	GREEN CHEMISTRY
	2011
卷号	13期号:10页码:2723-2726
关键词	NATIVE CHEMICAL LIGATION CATALYZED DOUBLE CARBOHYDROAMINATION AMIDE SYNTHESIS MILD AMIDATION ONE-POT OXIDATIVE AMIDATION GENERAL-SOLUTION ALDEHYDES ALCOHOLS EFFICIENT
ISSN号	1463-9262
通讯作者	Chen, H (reprint author), Wuhan Univ, Minist Educ, Key Lab Combinatorial Biosynthesis & Drug Discove, Wuhan 430071, Peoples R China
英文摘要	Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters in the presence of bis(trimethylsilyl) acetamide (BSA) has been developed. This general method provides convenient access to N-protected peptides in good yields under mild conditions and demonstrates a high tolerance to functionality.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	NATIVE CHEMICAL LIGATION ; CATALYZED DOUBLE CARBOHYDROAMINATION ; AMIDE SYNTHESIS ; MILD AMIDATION ; ONE-POT ; OXIDATIVE AMIDATION ; GENERAL-SOLUTION ; ALDEHYDES ; ALCOHOLS ; EFFICIENT
收录类别	SCI ; CCR
资助信息	National Mega Project on Major Drug Development[2009ZX09301-014-1]; NSFC[20872116, 91017005]; State Key Laboratory of Phytochemistry and Plant Resources in West China[P2010-KF10]
语种	英语
WOS记录号	WOS:000295579700017
公开日期	2012-07-25
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/14537]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Wuhan Univ, Minist Educ, Key Lab Combinatorial Biosynthesis & Drug Discove, Wuhan 430071, Peoples R China 2.Wuhan Univ, Sch Pharmaceut Sci, Wuhan 430071, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Chen, Hao,He, Maomao,Wang, Yaya,et al. Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters[J]. GREEN CHEMISTRY,2011,13(10):2723-2726.
APA	Chen, Hao.,He, Maomao.,Wang, Yaya.,Zhai, Linhui.,Cui, Yongbo.,...&Deng, Zixin.(2011).Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters.GREEN CHEMISTRY,13(10),2723-2726.
MLA	Chen, Hao,et al."Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters".GREEN CHEMISTRY 13.10(2011):2723-2726.

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