Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation
	Wang, BG; Hong, X; Li, L; Zhou, J; Hao, XJ
刊名	PLANTA MEDICA
	2000-08-01
卷号	66 期号:6 页码:511-515
关键词	Tsoongiodendron odorum Manglietiastrum sinicum Magnoliaceae chemical constituents inhibition platelet aggregation
英文摘要	Phytochemical investigations of Tsoongiodendron odorum and Manglietiastrum sinicum, both Magnoliaceae, led to the isolation of twenty compounds in total. Among them, one was a new sesquiterpene, 11-O-oleoyl-beta-eudesmol (2), and another, 1-(3,4-dimethoxypheny)-4-(3,4-methylenedioxyphenyl)- 2,3-dimethylbutane (12) was isolated as a natural product for the first time. Moreover, C-13-NMR spectral data of isoguaiacin (16) are reported here for the first time. Structure elucidations for compounds reported here were mainly based on their spectral data. The ethanolic extracts of T. odorum and M. sinicum, and six pure compounds, 4(15)-eudesmen-11-ol (beta-eudesmol) (1), 1 beta-hydroxy-4(15),11(13)-eudesmadien-12,6 alpha-olide (reynosin) (3), 3,11 (13)-eudesmadien-12,6 alpha-olide (alpha-cyclocostunolide) (5), erythro-1-(4-hydroxy-3-methoxyphenyl)-4-(3,4-methylene-dioxyphenyl)-2,3-dimethylbutane (11), nectandrin-B (18), and syringaresinol (19), displayed considerable inhibition against platelet aggregation induced by AA, by ADP, or by PAF.
学科主题	Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	LARREA-TRIDENTATA ; LIGNANS ; ACID ; MYRISTICACEAE ; CHEMISTRY
收录类别	SCI
语种	英语
WOS记录号	WOS:000088966100003
公开日期	2012-07-18
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/13637]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Wang, BG,Hong, X,Li, L,et al. Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation[J]. PLANTA MEDICA,2000,66(6):511-515.
APA	Wang, BG,Hong, X,Li, L,Zhou, J,&Hao, XJ.(2000).Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation.PLANTA MEDICA,66(6),511-515.
MLA	Wang, BG,et al."Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation".PLANTA MEDICA 66.6(2000):511-515.