Chiral detection using reusable fluorescent amylose-functionalized graphene

	Chiral detection using reusable fluorescent amylose-functionalized graphene
	Wei WL ; Qu KG ; Ren JS ; Qu XG
刊名	chemical science
	2011
卷号	2 期号:10 页码:2050-2056
关键词	MOLECULE FORCE SPECTROSCOPY ASPERGILLUS-NIGER GLUCOAMYLASE CARBON NANOTUBES CHROMATOGRAPHIC SEPARATION SENSING BIOMOLECULES INCLUSION COMPLEX LINEAR DEXTRINS HELICAL AMYLOSE TRYPTOPHAN OXIDE
ISSN号	2041-6520
通讯作者	qu xg
中文摘要	by using dna or a peptide as a common probe, graphene-based biosensing has made significant progress. however, to the best of our knowledge, a graphene-based chiral sensor has not been reported. chiroselective recognition is perhaps the most subtle to achieve because of the similarity of the optical enantiomers. therefore, besides using dna or peptides as probes, developing graphene-based sensors with chiral selectivity is highly desirable. here a reusable natural cheap polysaccharide, amylose-functionalized graphene was developed for highly sensitive and visual fluorescent chiral sensing. the detection sensitivity toward l-trp is over 100-times higher than that of recently reported electrochemical sensors and colorimetric sensors. in comparison with commonly used dna or peptides as a probe, natural amylose is more attractive because of its low cost, ready availability, simple manipulation and renewability. the specific selectivity for tryptophan (trp) enantiomers towards other essential amino acids allows potential chiroselective analysis of trp in complex samples such as biological fluids. this design can, in principle, be implemented for other slender target molecules that can form an inclusion complex with amylose.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000294503900026
公开日期	2012-06-12
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/45127]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Wei WL,Qu KG,Ren JS,et al. Chiral detection using reusable fluorescent amylose-functionalized graphene[J]. chemical science,2011,2(10):2050-2056.
APA	Wei WL,Qu KG,Ren JS,&Qu XG.(2011).Chiral detection using reusable fluorescent amylose-functionalized graphene.chemical science,2(10),2050-2056.
MLA	Wei WL,et al."Chiral detection using reusable fluorescent amylose-functionalized graphene".chemical science 2.10(2011):2050-2056.