Development of microfluidic based telemedicine for insulin detection

CORC > 沈阳自动化研究所 > 中国科学院沈阳自动化研究所 > 机器人学研究室

	Development of microfluidic based telemedicine for insulin detection
	Yao P(姚萍); Tung, Steve; Zhan ZK(詹志坤); Hua JN(化建宁); Dong ZL(董再励)
	2011
会议名称	1st Annual IEEE International Conference on Cyber Technology in Automation, Control, and Intelligent Systems, CYBER 2011
会议日期	March 20-23, 2011
会议地点	Kunming, China
关键词	Assays Chemical detection Chemiluminescence Fluidic devices Hydrogen peroxide Immunology Intelligent systems Internet protocols Microchannels Microfluidics Pumps Rural areas Telemedicine
页码	107-111
中文摘要	This article describes a prototype microfluidic system for insulin detection and exchanging the results digitally with physicians located off-site. The integrated polydimethysiloxane (PDMS) microfluidic system uses two pneumatic micropumps and one micromixer for chemiluminescent immunoassay, and a developed communications infrastructure for transferring the digital information from the assay site to a remote place for assistance by a trained medical professional. The expert can then directly provide control and diagnosis via the Internet. The insulin detection protocol is based on coupling the highly specific double-antibody sandwich immunoassay with the sensitive chemiluminescence of Luminol-Hydrogen Peroxide (H2O2). The peak value of the luminous intensity, recorded automatically by a photometer, is used as an indicator for the insulin concentration of the sample tested. The calibration curves of the insulin measurement were quantified and the insulin detection limit meets the common requirement of current clinical studies of diabetes. The combination of PDMS microfluidic devices and a communication strategy for exchanging information obtained from the assays with off-site diagnosticians offers new opportunities for point-of-care type health monitoring, especially in rural areas where patients must travel great distances to physicians to obtain diagnostic information that might be obtained more cost effectively by local, less-trained personnel.
收录类别	EI
产权排序	1
会议主办者	IEEE; IEEE Robotics and Automation Society; IEEE Nanotechnology Council; Yunan Provincial Science and Technology Department; Kunming University of Science and Technology
会议录	2011 IEEE International Conference on Cyber Technology in Automation, Control, and Intelligent Systems, CYBER 2011
会议录出版者	IEEE Computer Society
会议录出版地	Piscataway, NJ
语种	英语
ISBN号	978-1-61284-910-2
内容类型	会议论文
源URL	[http://ir.sia.cn/handle/173321/8669]
专题	沈阳自动化研究所_机器人学研究室
推荐引用方式 GB/T 7714	Yao P,Tung, Steve,Zhan ZK,et al. Development of microfluidic based telemedicine for insulin detection[C]. 见:1st Annual IEEE International Conference on Cyber Technology in Automation, Control, and Intelligent Systems, CYBER 2011. Kunming, China. March 20-23, 2011.