Oscillation, cooperativity, and intermediates in the self-repressing gene

	Oscillation, cooperativity, and intermediates in the self-repressing gene
	Lepzelter D ; Feng HD ; Wang J
刊名	chemical physics letters
	2010
卷号	490 期号:4-6 页码:216-220
关键词	MODEL PROTEIN ROBUST
ISSN号	0009-2614
通讯作者	wang j
中文摘要	biological oscillators are vital to living organisms, which use them as clocks for time-sensitive processes. however, much is unknown about mechanisms which can give rise to coherent oscillatory behavior, with few exceptions (e.g., explicitly delayed self-repressors and simple models of specific organisms' circadian clocks). we present what may be the simplest possible reliable gene network oscillator, a self-repressing gene. we show that binding cooperativity, which has not been considered in detail in this context, can combine with small numbers of intermediate steps to create coherent oscillation. we also note that noise blurs the line between oscillatory and non-oscillatory behavior. (c) 2010 elsevier b.v. all rights reserved.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000276822100021
公开日期	2012-06-06
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/43791]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Lepzelter D,Feng HD,Wang J. Oscillation, cooperativity, and intermediates in the self-repressing gene[J]. chemical physics letters,2010,490(4-6):216-220.
APA	Lepzelter D,Feng HD,&Wang J.(2010).Oscillation, cooperativity, and intermediates in the self-repressing gene.chemical physics letters,490(4-6),216-220.
MLA	Lepzelter D,et al."Oscillation, cooperativity, and intermediates in the self-repressing gene".chemical physics letters 490.4-6(2010):216-220.