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	Geographical Detectors-Based Health Risk Assessment and its Application in the Neural Tube Defects Study of the Heshun Region, China
	Wang J. F. ; Li X. H. ; Christakos G. ; Liao Y. L. ; Zhang T. ; Gu X. ; Zheng X. Y.
	2010
关键词	Geographical detectors Disease Determinants Spatial consistence Birth risk folic-acid birth-defects prevention epidemiology association population strategies dynamics model ntds
英文摘要	Physical environment, man-made pollution, nutrition and their mutual interactions can be major causes of human diseases. These disease determinants have distinct spatial distributions across geographical units, so that their adequate study involves the investigation of the associated geographical strata. We propose four geographical detectors based on spatial variation analysis of the geographical strata to assess the environmental risks of health: the risk detector indicates where the risk areas are; the factor detector identifies factors that are responsible for the risk; the ecological detector discloses relative importance between the factors; and the interaction detector reveals whether the risk factors interact or lead to disease independently. In a real-world study, the primary physical environment (watershed, lithozone and soil) was found to strongly control the neural tube defects (NTD) occurrences in the Heshun region (China). Basic nutrition (food) was found to be more important than man-made pollution (chemical fertilizer) in the control of the spatial NTD pattern. Ancient materials released from geological faults and subsequently spread along slopes dramatically increase the NTD risk. These findings constitute valuable input to disease intervention strategies in the region of interest.
出处	International Journal of Geographical Information Science
卷	24
期	1
页	107-127
收录类别	SCI
语种	英语
ISSN号	1365-8816
内容类型	SCI/SSCI论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/22924]
专题	地理科学与资源研究所_历年回溯文献
推荐引用方式 GB/T 7714	Wang J. F.,Li X. H.,Christakos G.,et al. Geographical Detectors-Based Health Risk Assessment and its Application in the Neural Tube Defects Study of the Heshun Region, China. 2010.

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