Cytotoxicity and wound healing properties of PVA/ws-chitosan/glycerol hydrogels made by irradiation followed by freeze-thawing

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	Cytotoxicity and wound healing properties of PVA/ws-chitosan/glycerol hydrogels made by irradiation followed by freeze-thawing
	Yang, XM ; Yang, K ; Wu, SW ; Chen, XL ; Yu, F ; Li, JG ; Ma, MW ; Zhu, ZY
刊名	RADIATION PHYSICS AND CHEMISTRY
	2010
卷号	79 期号:5 页码:6
关键词	Wound dressing Water soluble chitosan Poly(vinyl alcohol) Biocompatibility
ISSN号	0969-806X
通讯作者	Zhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China
英文摘要	Hydrogels based on poly(vinyl alcohol), water-soluble chitosan and glycerol made by irradiation followed by freeze-thawing were evaluated as wound dressing. MTT assay suggested that the extract of hydrogels was nontoxic towards L929 mouse fibroblasts. Compared to gauze dressing, the hydrogel can accelerate the healing process of full-thickness wounds in a rat model. Wounds treated with hydrogel healed at 11th day postoperatively and histological observation showed that mature epidermal architecture was formed. These indicate that it is a good wound dressing. (C) 2009 Elsevier Ltd. All rights reserved.
学科主题	Chemistry; Nuclear Science & Technology; Physics
收录类别	SCI
语种	英语
WOS记录号	WOS:000275997400008
公开日期	2012-04-11
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/6873]
专题	上海应用物理研究所_中科院上海应用物理研究所2004-2010年
推荐引用方式 GB/T 7714	Yang, XM,Yang, K,Wu, SW,et al. Cytotoxicity and wound healing properties of PVA/ws-chitosan/glycerol hydrogels made by irradiation followed by freeze-thawing[J]. RADIATION PHYSICS AND CHEMISTRY,2010,79(5):6.
APA	Yang, XM.,Yang, K.,Wu, SW.,Chen, XL.,Yu, F.,...&Zhu, ZY.(2010).Cytotoxicity and wound healing properties of PVA/ws-chitosan/glycerol hydrogels made by irradiation followed by freeze-thawing.RADIATION PHYSICS AND CHEMISTRY,79(5),6.
MLA	Yang, XM,et al."Cytotoxicity and wound healing properties of PVA/ws-chitosan/glycerol hydrogels made by irradiation followed by freeze-thawing".RADIATION PHYSICS AND CHEMISTRY 79.5(2010):6.